1foh: Difference between revisions

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-{{Seed}}
-[[Image:1foh.png|left|200px]]
-<!--
+==PHENOL HYDROXYLASE FROM TRICHOSPORON CUTANEUM==
-The line below this paragraph, containing "STRUCTURE_1foh", creates the "Structure Box" on the page.
+<StructureSection load='1foh' size='340' side='right'caption='[[1foh]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1foh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cutaneotrichosporon_cutaneum Cutaneotrichosporon cutaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FOH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FOH FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IPH:PHENOL'>IPH</scene></td></tr>
-{{STRUCTURE_1foh|  PDB=1foh  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1foh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1foh OCA], [https://pdbe.org/1foh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1foh RCSB], [https://www.ebi.ac.uk/pdbsum/1foh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1foh ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHHY_CUTCT PHHY_CUTCT] Hydroxylates phenol to catechol (PubMed:1429434, PubMed:4146224, PubMed:3203745, PubMed:2022646, PubMed:7858421, PubMed:7851397, PubMed:11591156). Phenol is the best substrate, but the enzyme also accepts isomeric diphenols, hydroxyl-, amino-, halogen- or methyl-substituted phenols and, to a lesser degree, cresols (PubMed:4146224, PubMed:17425111, PubMed:7851397).<ref>PMID:11591156</ref> <ref>PMID:1429434</ref> <ref>PMID:17425111</ref> <ref>PMID:2022646</ref> <ref>PMID:3203745</ref> <ref>PMID:4146224</ref> <ref>PMID:7851397</ref> <ref>PMID:7858421</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/1foh_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1foh ConSurf].
+<div style="clear:both"></div>
-===PHENOL HYDROXYLASE FROM TRICHOSPORON CUTANEUM===
+==See Also==
+*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_9634698}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 9634698 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Cutaneotrichosporon cutaneum]]
-{{ABSTRACT_PUBMED_9634698}}
+[[Category: Large Structures]]
+[[Category: Enroth C]]
-==About this Structure==
+[[Category: Lindqvist Y]]
-FOH is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trichosporon_cutaneum Trichosporon cutaneum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FOH OCA].
+[[Category: Neujahr H]]
+[[Category: Schneider G]]
-==Reference==
-<ref group="xtra">PMID:9634698</ref><references group="xtra"/>
-[[Category: Phenol 2-monooxygenase]]
-[[Category: Trichosporon cutaneum]]
-[[Category: Enroth, C.]]
-[[Category: Lindqvist, Y.]]
-[[Category: Neujahr, H.]]
-[[Category: Schneider, G.]]
-[[Category: Flavin]]
-[[Category: Monooxygenase]]
-[[Category: Oxidoreductase]]
-[[Category: Phenol hydroxylase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:32:12 2009''