1fl1: Difference between revisions

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{{Seed}}
[[Image:1fl1.png|left|200px]]


<!--
==KSHV PROTEASE==
The line below this paragraph, containing "STRUCTURE_1fl1", creates the "Structure Box" on the page.
<StructureSection load='1fl1' size='340' side='right'caption='[[1fl1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fl1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FL1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
{{STRUCTURE_1fl1|  PDB=1fl1  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fl1 OCA], [https://pdbe.org/1fl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fl1 RCSB], [https://www.ebi.ac.uk/pdbsum/1fl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fl1 ProSAT]</span></td></tr>
 
</table>
===KSHV PROTEASE===
== Function ==
 
[https://www.uniprot.org/uniprot/O36607_HHV8 O36607_HHV8]  
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_11041844}}, adds the Publication Abstract to the page
Check<jmol>
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  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1fl1_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_11041844}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1FL1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_8 Human herpesvirus 8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FL1 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fl1 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Functional consequences of the Kaposi's sarcoma-associated herpesvirus protease structure: regulation of activity and dimerization by conserved structural elements., Reiling KK, Pray TR, Craik CS, Stroud RM, Biochemistry. 2000 Oct 24;39(42):12796-803. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11041844 11041844]
</StructureSection>
[[Category: Human herpesvirus 8]]
[[Category: Human gammaherpesvirus 8]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Craik, C S.]]
[[Category: Craik CS]]
[[Category: Pray, T R.]]
[[Category: Pray TR]]
[[Category: Reiling, K K.]]
[[Category: Reiling KK]]
[[Category: Stroud, R M.]]
[[Category: Stroud RM]]
[[Category: Antiviral drug design]]
[[Category: Assemblin]]
[[Category: Capsid maturation]]
[[Category: Endopeptidase]]
[[Category: Serine protease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 03:25:33 2008''

Latest revision as of 10:15, 7 February 2024

KSHV PROTEASEKSHV PROTEASE

Structural highlights

1fl1 is a 2 chain structure with sequence from Human gammaherpesvirus 8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O36607_HHV8

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1fl1, resolution 2.20Å

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OCA
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