1f4h: Difference between revisions

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[[Image:1f4h.png|left|200px]]


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==E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC)==
The line below this paragraph, containing "STRUCTURE_1f4h", creates the "Structure Box" on the page.
<StructureSection load='1f4h' size='340' side='right'caption='[[1f4h]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1f4h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F4H FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1f4h|  PDB=1f4h |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f4h OCA], [https://pdbe.org/1f4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f4h RCSB], [https://www.ebi.ac.uk/pdbsum/1f4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f4h ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGAL_ECOLI BGAL_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f4/1f4h_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f4h ConSurf].
<div style="clear:both"></div>


===E. COLI (LACZ) BETA-GALACTOSIDASE (ORTHORHOMBIC)===
==See Also==
 
*[[Galactosidase 3D structures|Galactosidase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11045615}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11045615 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11045615}}
 
==About this Structure==
1F4H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F4H OCA].
 
==Reference==
High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation., Juers DH, Jacobson RH, Wigley D, Zhang XJ, Huber RE, Tronrud DE, Matthews BW, Protein Sci. 2000 Sep;9(9):1685-99. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11045615 11045615]
[[Category: Beta-galactosidase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Huber, R E.]]
[[Category: Huber RE]]
[[Category: Jacobson, R H.]]
[[Category: Jacobson RH]]
[[Category: Juers, D H.]]
[[Category: Juers DH]]
[[Category: Matthews, B W.]]
[[Category: Matthews BW]]
[[Category: Tronrud, D E.]]
[[Category: Tronrud DE]]
[[Category: Wigley, D.]]
[[Category: Wigley D]]
[[Category: Zhang, X J.]]
[[Category: Zhang XJ]]
[[Category: Alpha/beta barrel]]
[[Category: Beta supersandwich]]
[[Category: Fibronectin]]
[[Category: Jelly roll barrel]]
 
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