1f2u: Difference between revisions

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-{{Seed}}
-[[Image:1f2u.png|left|200px]]
-<!--
+==Crystal Structure of RAD50 ABC-ATPase==
-The line below this paragraph, containing "STRUCTURE_1f2u", creates the "Structure Box" on the page.
+<StructureSection load='1f2u' size='340' side='right'caption='[[1f2u]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1f2u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F2U FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-{{STRUCTURE_1f2u|  PDB=1f2u  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f2u OCA], [https://pdbe.org/1f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f2u RCSB], [https://www.ebi.ac.uk/pdbsum/1f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f2u ProSAT]</span></td></tr>
+</table>
-===CRYSTAL STRUCTURE OF RAD50 ABC-ATPASE===
+== Function ==
+[https://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
+== Evolutionary Conservation ==
-<!--
+[[Image:Consurf_key_small.gif|200px|right]]
-The line below this paragraph, {{ABSTRACT_PUBMED_10892749}}, adds the Publication Abstract to the page
+Check<jmol>
-(as it appears on PubMed at http://www.pubmed.gov), where 10892749 is the PubMed ID number.
+  <jmolCheckbox>
--->
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/1f2u_consurf.spt"</scriptWhenChecked>
-{{ABSTRACT_PUBMED_10892749}}
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
-==About this Structure==
+  </jmolCheckbox>
-F2U is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F2U OCA].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f2u ConSurf].
+<div style="clear:both"></div>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:10892749</ref><references group="xtra"/>
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Pyrococcus furiosus]]
-[[Category: Craig, L.]]
+[[Category: Craig L]]
-[[Category: Hopfner, K P.]]
+[[Category: Hopfner KP]]
-[[Category: Karcher, A.]]
+[[Category: Karcher A]]
-[[Category: Shin, D S.]]
+[[Category: Shin DS]]
-[[Category: Abc-atpase]]
-[[Category: Dna double-strand break repair]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:24:54 2009''