1evw: Difference between revisions

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[[Image:1evw.png|left|200px]]


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==L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.==
The line below this paragraph, containing "STRUCTURE_1evw", creates the "Structure Box" on the page.
<StructureSection load='1evw' size='340' side='right'caption='[[1evw]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1evw]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Physarum_polycephalum Physarum polycephalum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EVW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1evw|  PDB=1evw  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1evw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1evw OCA], [https://pdbe.org/1evw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1evw RCSB], [https://www.ebi.ac.uk/pdbsum/1evw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1evw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PPO1_PHYPO PPO1_PHYPO] Mediates the homing of a group I intron in the ribosomal DNA. Makes a four-base staggered cut in its ribosomal DNA target sequence.


===L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.===
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
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{{ABSTRACT_PUBMED_10891275}}
 
==About this Structure==
1EVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Physarum_polycephalum Physarum polycephalum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EVW OCA].
 
==Reference==
Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site., Galburt EA, Chadsey MS, Jurica MS, Chevalier BS, Erho D, Tang W, Monnat RJ Jr, Stoddard BL, J Mol Biol. 2000 Jul 21;300(4):877-87. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10891275 10891275]
[[Category: Physarum polycephalum]]
[[Category: Physarum polycephalum]]
[[Category: Single protein]]
[[Category: Chevalier BS]]
[[Category: Chevalier, B S.]]
[[Category: Erho D]]
[[Category: Erho, D.]]
[[Category: Galburt EA]]
[[Category: Galburt, E A.]]
[[Category: Jurica MS]]
[[Category: Jurica, M S.]]
[[Category: Stoddard BL]]
[[Category: Stoddard, B L.]]
[[Category: Bent dna]]
[[Category: C-terminal exchanged dimer interface]]
[[Category: Dna binding b-sheet]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 02:06:10 2008''

Latest revision as of 10:07, 7 February 2024

L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.L116A MUTANT OF THE HOMING ENDONUCLEASE I-PPOI COMPLEXED TO HOMING SITE DNA.

Structural highlights

1evw is a 12 chain structure with sequence from Physarum polycephalum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.1Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PPO1_PHYPO Mediates the homing of a group I intron in the ribosomal DNA. Makes a four-base staggered cut in its ribosomal DNA target sequence.

See Also

1evw, resolution 3.10Å

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