1etk: Difference between revisions

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-{{Seed}}
-[[Image:1etk.png|left|200px]]
-<!--
+==THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A==
-The line below this paragraph, containing "STRUCTURE_1etk", creates the "Structure Box" on the page.
+<StructureSection load='1etk' size='340' side='right'caption='[[1etk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1etk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ETK FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1etk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1etk OCA], [https://pdbe.org/1etk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1etk RCSB], [https://www.ebi.ac.uk/pdbsum/1etk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1etk ProSAT]</span></td></tr>
-{{STRUCTURE_1etk|  PDB=1etk  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref> <ref>PMID:8836178</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/1etk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1etk ConSurf].
+<div style="clear:both"></div>
-===THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A===
+==See Also==
+*[[FIS protein|FIS protein]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_11183780}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 11183780 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_11183780}}
-==About this Structure==
-ETK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETK OCA].
-==Reference==
-Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties., Cheng YS, Yang WZ, Johnson RC, Yuan HS, J Mol Biol. 2000 Oct 6;302(5):1139-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11183780 11183780]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Cheng, Y S.]]
+[[Category: Cheng YS]]
-[[Category: Johnson, R C.]]
+[[Category: Johnson RC]]
-[[Category: Yang, W Z.]]
+[[Category: Yang WZ]]
-[[Category: Yuan, H S.]]
+[[Category: Yuan HS]]
-[[Category: Dna-binding protein]]
-[[Category: Transcriptional activation region]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:57:18 2008''