1etk: Difference between revisions

Latest revision as of 10:06, 7 February 2024

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68ATHE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A

Structural highlights

1etk is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.1Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FIS_ECOLI Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Ross W, Thompson JF, Newlands JT, Gourse RL. E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. EMBO J. 1990 Nov;9(11):3733-42. PMID:2209559
↑ Wold S, Crooke E, Skarstad K. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 1996 Sep 15;24(18):3527-32. PMID:8836178

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OCA

[1] Ross W, Thompson JF, Newlands JT, Gourse RL. E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. EMBO J. 1990 Nov;9(11):3733-42. PMID:2209559

[2] Wold S, Crooke E, Skarstad K. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 1996 Sep 15;24(18):3527-32. PMID:8836178

[1]

[2]

@@ Line 1: / Line 1: @@
-[[Image:1etk.png|left|200px]]
-{{STRUCTURE_1etk|  PDB=1etk  |  SCENE=  }}
+==THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A==
+<StructureSection load='1etk' size='340' side='right'caption='[[1etk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1etk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ETK FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1etk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1etk OCA], [https://pdbe.org/1etk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1etk RCSB], [https://www.ebi.ac.uk/pdbsum/1etk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1etk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref> <ref>PMID:8836178</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/et/1etk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1etk ConSurf].
+<div style="clear:both"></div>
-===THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A===
+==See Also==
+*[[FIS protein|FIS protein]]
+== References ==
-==About this Structure==
+<references/>
-[[1etk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ETK OCA].
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:011183780</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Cheng, Y S.]]
+[[Category: Large Structures]]
-[[Category: Johnson, R C.]]
+[[Category: Cheng YS]]
-[[Category: Yang, W Z.]]
+[[Category: Johnson RC]]
-[[Category: Yuan, H S.]]
+[[Category: Yang WZ]]
-[[Category: Dna-binding protein]]
+[[Category: Yuan HS]]
-[[Category: Transcription activator]]
-[[Category: Transcriptional activation region]]

1etk: Difference between revisions

Latest revision as of 10:06, 7 February 2024

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68ATHE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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1etk: Difference between revisions

Latest revision as of 10:06, 7 February 2024

THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68ATHE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A

Structural highlights

Function

Evolutionary Conservation

See Also

References

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