1es4: Difference between revisions

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[[Image:1es4.png|left|200px]]


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==C98N mutant of streptomyces K15 DD-transpeptidase==
The line below this paragraph, containing "STRUCTURE_1es4", creates the "Structure Box" on the page.
<StructureSection load='1es4' size='340' side='right'caption='[[1es4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1es4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_sp._K15 Streptomyces sp. K15]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ES4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ES4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1es4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1es4 OCA], [https://pdbe.org/1es4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1es4 RCSB], [https://www.ebi.ac.uk/pdbsum/1es4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1es4 ProSAT]</span></td></tr>
{{STRUCTURE_1es4| PDB=1es4 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DACX_STRSK DACX_STRSK] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/es/1es4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1es4 ConSurf].
<div style="clear:both"></div>


===C98N mutant of streptomyces K15 DD-transpeptidase===
==See Also==
 
*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
 
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12627955}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 12627955 is the PubMed ID number.
[[Category: Large Structures]]
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[[Category: Streptomyces sp. K15]]
{{ABSTRACT_PUBMED_12627955}}
[[Category: Charlier P]]
 
[[Category: Fonze E]]
==About this Structure==
1ES4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp. Streptomyces sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ES4 OCA].
 
==Reference==
Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis., Rhazi N, Charlier P, Dehareng D, Engher D, Vermeire M, Frere JM, Nguyen-Disteche M, Fonze E, Biochemistry. 2003 Mar 18;42(10):2895-906. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12627955 12627955]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Single protein]]
[[Category: Streptomyces sp.]]
[[Category: Charlier, P.]]
[[Category: Fonze, E.]]
[[Category: Beta-lactamase]]
[[Category: Dd-transpeptidase]]
[[Category: Hydrolase carboxypeptidase]]
[[Category: Penicillin-binding]]
[[Category: Serine peptidase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:47:25 2008''

Latest revision as of 10:06, 7 February 2024

C98N mutant of streptomyces K15 DD-transpeptidaseC98N mutant of streptomyces K15 DD-transpeptidase

Structural highlights

1es4 is a 1 chain structure with sequence from Streptomyces sp. K15. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DACX_STRSK Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1es4, resolution 1.90Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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