1en4: Difference between revisions

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-[[Image:1en4.png|left|200px]]
-{{STRUCTURE_1en4|  PDB=1en4  |  SCENE=  }}
+==CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT==
+<StructureSection load='1en4' size='340' side='right'caption='[[1en4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1en4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EN4 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_11141052}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1en4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1en4 OCA], [https://pdbe.org/1en4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1en4 RCSB], [https://www.ebi.ac.uk/pdbsum/1en4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1en4 ProSAT]</span></td></tr>
-[[1en4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EN4 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SODM_ECOLI SODM_ECOLI] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/en/1en4_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1en4 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Superoxide Dismutase|Superoxide Dismutase]]
+*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:011141052</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Superoxide dismutase]]
+[[Category: Large Structures]]
-[[Category: Baker, E N.]]
+[[Category: Baker EN]]
-[[Category: Edwards, R A.]]
+[[Category: Edwards RA]]
-[[Category: Jameson, G B.]]
+[[Category: Jameson GB]]
-[[Category: Whittaker, J W.]]
+[[Category: Whittaker JW]]
-[[Category: Whittaker, M M.]]
+[[Category: Whittaker MM]]
-[[Category: Manganese superoxide dismutase]]
-[[Category: Mutant]]
-[[Category: Oxidoreductase]]
-[[Category: Proton shuttle]]
-[[Category: Q146h]]