1elw: Difference between revisions

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-[[Image:1elw.png|left|200px]]
-{{STRUCTURE_1elw|  PDB=1elw  |  SCENE=  }}
+==Crystal structure of the TPR1 domain of HOP in complex with a HSC70 peptide==
+<StructureSection load='1elw' size='340' side='right'caption='[[1elw]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1elw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ELW FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1elw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1elw OCA], [https://pdbe.org/1elw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1elw RCSB], [https://www.ebi.ac.uk/pdbsum/1elw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1elw ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/STIP1_HUMAN STIP1_HUMAN] Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/1elw_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1elw ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of the TPR1 domain of HOP in complex with a HSC70 peptide===
+==See Also==
+*[[HOP protein|HOP protein]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[1elw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELW OCA].
-==Reference==
-<ref group="xtra">PMID:010786835</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
-[[Category: Brinker, A.]]
+[[Category: Large Structures]]
-[[Category: Hartl, F U.]]
+[[Category: Brinker A]]
-[[Category: Moarefi, I.]]
+[[Category: Hartl FU]]
-[[Category: Scheufler, C.]]
+[[Category: Moarefi I]]
-[[Category: Chaperone]]
+[[Category: Scheufler C]]
-[[Category: Helical repeat]]
-[[Category: Hop]]
-[[Category: Hsc70]]
-[[Category: Hsp70]]
-[[Category: Peptide-complex]]
-[[Category: Protein binding]]
-[[Category: Tpr-domain]]