1ejy: Difference between revisions

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[[Image:1ejy.png|left|200px]]


{{STRUCTURE_1ejy|  PDB=1ejy  |  SCENE=  }}
==MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX==
 
<StructureSection load='1ejy' size='340' side='right'caption='[[1ejy]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
===MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1ejy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJY FirstGlance]. <br>
{{ABSTRACT_PUBMED_10764582}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ejy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ejy OCA], [https://pdbe.org/1ejy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ejy RCSB], [https://www.ebi.ac.uk/pdbsum/1ejy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ejy ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1ejy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJY OCA].  
== Function ==
[https://www.uniprot.org/uniprot/NUPL_XENLA NUPL_XENLA] Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Nucleoplasmin is an acidic protein which is able to assemble nucleosomes by binding histones and transferring them to DNA.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/1ejy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ejy ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Importin 3D structures|Importin 3D structures]]
*[[Nucleoplasmin|Nucleoplasmin]]
*[[Nucleoplasmin|Nucleoplasmin]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010764582</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Fontes, M R.]]
[[Category: Xenopus laevis]]
[[Category: Kobe, B.]]
[[Category: Fontes MR]]
[[Category: Teh, T.]]
[[Category: Kobe B]]
[[Category: Hydrolase-peptide complex]]
[[Category: Teh T]]
[[Category: Importin aplpha/karyopherin alpha]]
[[Category: Nucleoplasmin]]
[[Category: Protein binding]]

Latest revision as of 10:03, 7 February 2024

MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEXMOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX

Structural highlights

1ejy is a 2 chain structure with sequence from Mus musculus and Xenopus laevis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NUPL_XENLA Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Nucleoplasmin is an acidic protein which is able to assemble nucleosomes by binding histones and transferring them to DNA.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ejy, resolution 2.90Å

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