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[[Image:1ej8.png|left|200px]]


{{STRUCTURE_1ej8|  PDB=1ej8  |  SCENE=  }}
==CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION==
 
<StructureSection load='1ej8' size='340' side='right'caption='[[1ej8]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
===CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1ej8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJ8 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
[[1ej8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ8 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ej8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ej8 OCA], [https://pdbe.org/1ej8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ej8 RCSB], [https://www.ebi.ac.uk/pdbsum/1ej8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ej8 ProSAT]</span></td></tr>
 
</table>
==Reference==
== Function ==
<ref group="xtra">PMID:010736160</ref><references group="xtra"/>
[https://www.uniprot.org/uniprot/CCS1_YEAST CCS1_YEAST] Copper chaperone for apo superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to apo-SOD1.<ref>PMID:9295278</ref>  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/1ej8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ej8 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Demeler, B.]]
[[Category: Demeler B]]
[[Category: Hall, L T.]]
[[Category: Hall LT]]
[[Category: Hansen, J C.]]
[[Category: Hansen JC]]
[[Category: Hart, P J.]]
[[Category: Hart PJ]]
[[Category: Holloway, S P.]]
[[Category: Holloway SP]]
[[Category: Lyons, T J.]]
[[Category: Lyons TJ]]
[[Category: Nersissian, A M.]]
[[Category: Nersissian AM]]
[[Category: Sanchez, R J.]]
[[Category: Sanchez RJ]]
[[Category: Schirf, V.]]
[[Category: Schirf V]]
[[Category: Stine, J E.]]
[[Category: Stine JE]]
[[Category: Valentine, J S.]]
[[Category: Valentine JS]]
[[Category: Zhu, H.]]
[[Category: Zhu H]]
[[Category: Beta barrel]]
[[Category: Chaperone]]
[[Category: Copper chaperone for sod]]
[[Category: Domain 2]]

Latest revision as of 10:03, 7 February 2024

CRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTIONCRYSTAL STRUCTURE OF DOMAIN 2 OF THE YEAST COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE (LYS7) AT 1.55 A RESOLUTION

Structural highlights

1ej8 is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.55Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CCS1_YEAST Copper chaperone for apo superoxide dismutase 1 (SOD1). Binds copper ions and delivers them specifically to apo-SOD1.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Culotta VC, Klomp LW, Strain J, Casareno RL, Krems B, Gitlin JD. The copper chaperone for superoxide dismutase. J Biol Chem. 1997 Sep 19;272(38):23469-72. PMID:9295278

1ej8, resolution 1.55Å

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