1eae: Difference between revisions

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-[[Image:1eae.png|left|200px]]
-{{STRUCTURE_1eae|  PDB=1eae  |  SCENE=  }}
+==ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX==
+<StructureSection load='1eae' size='340' side='right'caption='[[1eae]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-===ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1eae]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EAE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EAE FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LPM:6,8-DIMERCAPTO-OCTANOIC+ACID+AMIDE'>LPM</scene></td></tr>
-[[1eae]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EAE OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eae FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eae OCA], [https://pdbe.org/1eae PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eae RCSB], [https://www.ebi.ac.uk/pdbsum/1eae PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eae ProSAT]</span></td></tr>
+</table>
-==Reference==
+== Function ==
-<ref group="xtra">PMID:008471601</ref><references group="xtra"/>
+[https://www.uniprot.org/uniprot/ODP2_AZOVI ODP2_AZOVI] The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ea/1eae_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eae ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Azotobacter vinelandii]]
-[[Category: Dihydrolipoyllysine-residue acetyltransferase]]
+[[Category: Large Structures]]
-[[Category: Hol, W G.J.]]
+[[Category: Hol WGJ]]
-[[Category: Mattevi, A.]]
+[[Category: Mattevi A]]
-[[Category: Dihydrolipoamide acetyltransferase]]