1dut: Difference between revisions

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{{Seed}}
[[Image:1dut.png|left|200px]]


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==FIV DUTP PYROPHOSPHATASE==
The line below this paragraph, containing "STRUCTURE_1dut", creates the "Structure Box" on the page.
<StructureSection load='1dut' size='340' side='right'caption='[[1dut]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus_(isolate_Petaluma) Feline immunodeficiency virus (isolate Petaluma)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DUT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1dut| PDB=1dut |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dut OCA], [https://pdbe.org/1dut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dut RCSB], [https://www.ebi.ac.uk/pdbsum/1dut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dut ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/1dut_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dut ConSurf].
<div style="clear:both"></div>


===FIV DUTP PYROPHOSPHATASE===
==See Also==
 
*[[DUTPase 3D structures|DUTPase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_8976551}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 8976551 is the PubMed ID number.
[[Category: Elder JH]]
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[[Category: Hasselkus-Light C]]
{{ABSTRACT_PUBMED_8976551}}
[[Category: Laco GS]]
 
[[Category: Mcree DE]]
==About this Structure==
[[Category: Prasad GS]]
1DUT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUT OCA].
[[Category: Stout CD]]
 
[[Category: Stura EA]]
==Reference==
Crystal structure of dUTP pyrophosphatase from feline immunodeficiency virus., Prasad GS, Stura EA, McRee DE, Laco GS, Hasselkus-Light C, Elder JH, Stout CD, Protein Sci. 1996 Dec;5(12):2429-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8976551 8976551]
[[Category: Single protein]]
[[Category: Viruses]]
[[Category: DUTP diphosphatase]]
[[Category: Elder, J H.]]
[[Category: Hasselkus-Light, C.]]
[[Category: Laco, G S.]]
[[Category: Mcree, D E.]]
[[Category: Prasad, G S.]]
[[Category: Stout, C D.]]
[[Category: Stura, E A.]]
[[Category: Acid anhydride hydrolase]]
[[Category: Aspartyl protease]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Nucleotide metabolism]]
[[Category: Polyprotein]]
[[Category: Rna-directed dna polymerase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:39:03 2008''

Latest revision as of 09:59, 7 February 2024

FIV DUTP PYROPHOSPHATASEFIV DUTP PYROPHOSPHATASE

Structural highlights

1dut is a 2 chain structure with sequence from Feline immunodeficiency virus (isolate Petaluma). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

POL_FIVPE During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1dut, resolution 1.90Å

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