1dut: Difference between revisions

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-[[Image:1dut.png|left|200px]]
-{{STRUCTURE_1dut|  PDB=1dut  |  SCENE=  }}
+==FIV DUTP PYROPHOSPHATASE==
+<StructureSection load='1dut' size='340' side='right'caption='[[1dut]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===FIV DUTP PYROPHOSPHATASE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1dut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus_(isolate_Petaluma) Feline immunodeficiency virus (isolate Petaluma)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DUT FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8976551}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dut OCA], [https://pdbe.org/1dut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dut RCSB], [https://www.ebi.ac.uk/pdbsum/1dut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dut ProSAT]</span></td></tr>
-[[1dut]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUT OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/du/1dut_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dut ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
+*[[DUTPase 3D structures|DUTPase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:008976551</ref><ref group="xtra">PMID:009878436</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Feline immunodeficiency virus]]
+[[Category: Elder JH]]
-[[Category: DUTP diphosphatase]]
+[[Category: Hasselkus-Light C]]
-[[Category: Elder, J H.]]
+[[Category: Laco GS]]
-[[Category: Hasselkus-Light, C.]]
+[[Category: Mcree DE]]
-[[Category: Laco, G S.]]
+[[Category: Prasad GS]]
-[[Category: Mcree, D E.]]
+[[Category: Stout CD]]
-[[Category: Prasad, G S.]]
+[[Category: Stura EA]]
-[[Category: Stout, C D.]]
-[[Category: Stura, E A.]]
-[[Category: Acid anhydride hydrolase]]
-[[Category: Aspartyl protease]]
-[[Category: Endonuclease]]
-[[Category: Hydrolase]]
-[[Category: Nucleotide metabolism]]
-[[Category: Polyprotein]]
-[[Category: Rna-directed dna polymerase]]