1dsx: Difference between revisions
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==KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT== | |||
<StructureSection load='1dsx' size='340' side='right'caption='[[1dsx]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1dsx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DSX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dsx OCA], [https://pdbe.org/1dsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dsx RCSB], [https://www.ebi.ac.uk/pdbsum/1dsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dsx ProSAT]</span></td></tr> | |||
== | </table> | ||
[[1dsx]] is a 8 chain structure | == Function == | ||
[https://www.uniprot.org/uniprot/KCNA2_RAT KCNA2_RAT] Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.<ref>PMID:7544443</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/1dsx_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dsx ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Potassium | *[[Potassium channel 3D structures|Potassium channel 3D structures]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Avelar | [[Category: Avelar A]] | ||
[[Category: Berger | [[Category: Berger JM]] | ||
[[Category: Jan | [[Category: Jan LY]] | ||
[[Category: Jan | [[Category: Jan YN]] | ||
[[Category: Lin | [[Category: Lin Y-F]] | ||
[[Category: Minor | [[Category: Minor Jr DL]] | ||
[[Category: Mobley | [[Category: Mobley BC]] | ||
Latest revision as of 09:58, 7 February 2024
KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANTKV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT
Structural highlights
FunctionKCNA2_RAT Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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