1dsp: Difference between revisions

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[[Image:1dsp.png|left|200px]]


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==CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 7, ROOM TEMPERATURE.==
The line below this paragraph, containing "STRUCTURE_1dsp", creates the "Structure Box" on the page.
<StructureSection load='1dsp' size='340' side='right'caption='[[1dsp]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dsp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DSP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
{{STRUCTURE_1dsp| PDB=1dsp |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dsp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dsp OCA], [https://pdbe.org/1dsp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dsp RCSB], [https://www.ebi.ac.uk/pdbsum/1dsp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dsp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CCPR_YEAST CCPR_YEAST] Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ds/1dsp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dsp ConSurf].
<div style="clear:both"></div>


===CYTOCHROME C PEROXIDASE H175G MUTANT, IMIDAZOLE COMPLEX AT PH 7, ROOM TEMPERATURE.===
==See Also==
 
*[[Cytochrome c peroxidase 3D structures|Cytochrome c peroxidase 3D structures]]
 
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The line below this paragraph, {{ABSTRACT_PUBMED_11170452}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 11170452 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11170452}}
 
==About this Structure==
1DSP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DSP OCA].
 
==Reference==
Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure., Hirst J, Wilcox SK, Williams PA, Blankenship J, McRee DE, Goodin DB, Biochemistry. 2001 Feb 6;40(5):1265-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11170452 11170452]
[[Category: Cytochrome-c peroxidase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Goodin DB]]
[[Category: Goodin, D B.]]
[[Category: Hirst J]]
[[Category: Hirst, J.]]
[[Category: McRee DE]]
[[Category: McRee, D E.]]
[[Category: Wilcox SK]]
[[Category: Wilcox, S K.]]
[[Category: Williams PA]]
[[Category: Williams, P A.]]
[[Category: Cavity mutant]]
[[Category: Heme enzyme]]
[[Category: Ligand binding]]
[[Category: Peroxidase]]
 
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