1dpt: Difference between revisions

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[[Image:1dpt.png|left|200px]]


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==D-DOPACHROME TAUTOMERASE==
The line below this paragraph, containing "STRUCTURE_1dpt", creates the "Structure Box" on the page.
<StructureSection load='1dpt' size='340' side='right'caption='[[1dpt]], [[Resolution|resolution]] 1.54&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dpt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.54&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpt OCA], [https://pdbe.org/1dpt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpt RCSB], [https://www.ebi.ac.uk/pdbsum/1dpt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpt ProSAT]</span></td></tr>
{{STRUCTURE_1dpt| PDB=1dpt |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DOPD_HUMAN DOPD_HUMAN] Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dp/1dpt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dpt ConSurf].
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===D-DOPACHROME TAUTOMERASE===
==See Also==
 
*[[Macrophage inhibitory factor 3D structures|Macrophage inhibitory factor 3D structures]]
 
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 10079069 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10079069}}
 
==About this Structure==
1DPT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPT OCA].
 
==Reference==
Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 A resolution., Sugimoto H, Taniguchi M, Nakagawa A, Tanaka I, Suzuki M, Nishihira J, Biochemistry. 1999 Mar 16;38(11):3268-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10079069 10079069]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Nakagawa, A.]]
[[Category: Nakagawa A]]
[[Category: Sugimoto, H.]]
[[Category: Sugimoto H]]
[[Category: Tanaka, I.]]
[[Category: Tanaka I]]
[[Category: Taniguchi, M.]]
[[Category: Taniguchi M]]
[[Category: Cytokine]]
[[Category: Growth factor]]
[[Category: Tautomerase]]
 
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