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[[Image:1dpn.gif|left|200px]]


{{Structure
==B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE==
|PDB= 1dpn |SIZE=350|CAPTION= <scene name='initialview01'>1dpn</scene>, resolution 0.95&Aring;
<StructureSection load='1dpn' size='340' side='right'caption='[[1dpn]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TAF:2&#39;-DEOXY-2&#39;-FLUORO-ARABINO-FURANOSYL+THYMINE-5&#39;-PHOSPHATE'>TAF</scene>
<table><tr><td colspan='2'>[[1dpn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPN FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
|DOMAIN=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpn OCA], [https://pdbe.org/1dpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpn RCSB], [https://www.ebi.ac.uk/pdbsum/1dpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpn ProSAT]</span></td></tr>
|RELATEDENTRY=
</table>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpn OCA], [http://www.ebi.ac.uk/pdbsum/1dpn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1dpn RCSB]</span>
__TOC__
}}
</StructureSection>
 
[[Category: Large Structures]]
'''B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE'''
[[Category: An H]]
 
[[Category: Dan Cook P]]
 
[[Category: Egli M]]
==Overview==
[[Category: Joachimiak A]]
We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.
[[Category: Maier MA]]
 
[[Category: Manoharan M]]
==About this Structure==
[[Category: Miller R]]
1DPN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPN OCA].
[[Category: Minasov G]]
 
[[Category: Sanishvili R]]
==Reference==
[[Category: Teplova M]]
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10699842 10699842]
[[Category: Tereshko V]]
[[Category: Protein complex]]
[[Category: Weeks CM]]
[[Category: An, H.]]
[[Category: Cook, P Dan.]]
[[Category: Egli, M.]]
[[Category: Joachimiak, A.]]
[[Category: Maier, M A.]]
[[Category: Manoharan, M.]]
[[Category: Miller, R.]]
[[Category: Minasov, G.]]
[[Category: Sanishvili, R.]]
[[Category: Teplova, M.]]
[[Category: Tereshko, V.]]
[[Category: Weeks, C M.]]
[[Category: 0 95 a resolution structure]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:46:11 2008''

Latest revision as of 09:57, 7 February 2024

B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINEB-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE

Structural highlights

1dpn is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.95Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

1dpn, resolution 0.95Å

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