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[[Image:1dpn.gif|left|200px]]<br /><applet load="1dpn" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1dpn, resolution 0.95&Aring;" />
'''B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE'''<br />


==Overview==
==B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE==
We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.
<StructureSection load='1dpn' size='340' side='right'caption='[[1dpn]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1dpn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPN FirstGlance]. <br>
1DPN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPN OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpn OCA], [https://pdbe.org/1dpn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpn RCSB], [https://www.ebi.ac.uk/pdbsum/1dpn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpn ProSAT]</span></td></tr>
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10699842 10699842]
</table>
[[Category: Protein complex]]
__TOC__
[[Category: An, H.]]
</StructureSection>
[[Category: Cook, P Dan.]]
[[Category: Large Structures]]
[[Category: Egli, M.]]
[[Category: An H]]
[[Category: Joachimiak, A.]]
[[Category: Dan Cook P]]
[[Category: Maier, M A.]]
[[Category: Egli M]]
[[Category: Manoharan, M.]]
[[Category: Joachimiak A]]
[[Category: Miller, R.]]
[[Category: Maier MA]]
[[Category: Minasov, G.]]
[[Category: Manoharan M]]
[[Category: Sanishvili, R.]]
[[Category: Miller R]]
[[Category: Teplova, M.]]
[[Category: Minasov G]]
[[Category: Tereshko, V.]]
[[Category: Sanishvili R]]
[[Category: Weeks, C M.]]
[[Category: Teplova M]]
[[Category: MG]]
[[Category: Tereshko V]]
[[Category: 0 95 a resolution structure]]
[[Category: Weeks CM]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:19:04 2008''

Latest revision as of 09:57, 7 February 2024

B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINEB-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE

Structural highlights

1dpn is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.95Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

1dpn, resolution 0.95Å

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