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[[Image:1dpl.gif|left|200px]]


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==A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE==
The line below this paragraph, containing "STRUCTURE_1dpl", creates the "Structure Box" on the page.
<StructureSection load='1dpl' size='340' side='right'caption='[[1dpl]], [[Resolution|resolution]] 0.83&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.83&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=T23:2-O-METHYL-3-METHYL-3-DEOXY-ARABINOFURANOSYL-THYMINE-5-PHOSPHATE'>T23</scene></td></tr>
{{STRUCTURE_1dpl|  PDB=1dpl  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpl OCA], [https://pdbe.org/1dpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpl RCSB], [https://www.ebi.ac.uk/pdbsum/1dpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpl ProSAT]</span></td></tr>
 
</table>
'''A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE'''
__TOC__
 
</StructureSection>
 
[[Category: Large Structures]]
==Overview==
[[Category: An H]]
We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.
[[Category: Dan Cook P]]
 
[[Category: Egli M]]
==About this Structure==
[[Category: Joachimiak A]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA].  
[[Category: Maier MA]]
 
[[Category: Manoharan M]]
==Reference==
[[Category: Miller R]]
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution., Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M, Biopolymers. 1998;48(4):234-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10699842 10699842]
[[Category: Minasov G]]
[[Category: An, H.]]
[[Category: Sanishvili R]]
[[Category: Cook, P Dan.]]
[[Category: Teplova M]]
[[Category: Egli, M.]]
[[Category: Tereshko V]]
[[Category: Joachimiak, A.]]
[[Category: Weeks CM]]
[[Category: Maier, M A.]]
[[Category: Manoharan, M.]]
[[Category: Miller, R.]]
[[Category: Minasov, G.]]
[[Category: Sanishvili, R.]]
[[Category: Teplova, M.]]
[[Category: Tereshko, V.]]
[[Category: Weeks, C M.]]
[[Category: Deoxyribonucleic acid]]
[[Category: Modified a-decamer at 0 83 a resolution]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 14:07:14 2008''

Latest revision as of 09:57, 7 February 2024

A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINEA-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE

Structural highlights

1dpl is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.83Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

1dpl, resolution 0.83Å

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