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==A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE==
==A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE==
<StructureSection load='1dpl' size='340' side='right' caption='[[1dpl]], [[Resolution|resolution]] 0.83&Aring;' scene=''>
<StructureSection load='1dpl' size='340' side='right'caption='[[1dpl]], [[Resolution|resolution]] 0.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1dpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DPL FirstGlance]. <br>
<table><tr><td colspan='2'>[[1dpl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DPL FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.83&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=T23:2-O-METHYL-3-METHYL-3-DEOXY-ARABINOFURANOSYL-THYMINE-5-PHOSPHATE'>T23</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=T23:2-O-METHYL-3-METHYL-3-DEOXY-ARABINOFURANOSYL-THYMINE-5-PHOSPHATE'>T23</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dpl RCSB], [http://www.ebi.ac.uk/pdbsum/1dpl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dpl OCA], [https://pdbe.org/1dpl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dpl RCSB], [https://www.ebi.ac.uk/pdbsum/1dpl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dpl ProSAT]</span></td></tr>
<table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.
 
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.,Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M Biopolymers. 1998;48(4):234-52. PMID:10699842<ref>PMID:10699842</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: An, H.]]
[[Category: Large Structures]]
[[Category: Cook, P Dan.]]
[[Category: An H]]
[[Category: Egli, M.]]
[[Category: Dan Cook P]]
[[Category: Joachimiak, A.]]
[[Category: Egli M]]
[[Category: Maier, M A.]]
[[Category: Joachimiak A]]
[[Category: Manoharan, M.]]
[[Category: Maier MA]]
[[Category: Miller, R.]]
[[Category: Manoharan M]]
[[Category: Minasov, G.]]
[[Category: Miller R]]
[[Category: Sanishvili, R.]]
[[Category: Minasov G]]
[[Category: Teplova, M.]]
[[Category: Sanishvili R]]
[[Category: Tereshko, V.]]
[[Category: Teplova M]]
[[Category: Weeks, C M.]]
[[Category: Tereshko V]]
[[Category: Deoxyribonucleic acid]]
[[Category: Weeks CM]]
[[Category: Dna]]
[[Category: Modified a-decamer at 0 83 a resolution]]

Latest revision as of 09:57, 7 February 2024

A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINEA-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE

Structural highlights

1dpl is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 0.83Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

1dpl, resolution 0.83Å

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