1dkw: Difference between revisions

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[[Image:1dkw.png|left|200px]]


{{STRUCTURE_1dkw|  PDB=1dkw  |  SCENE=  }}
==CRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITE==
 
<StructureSection load='1dkw' size='340' side='right'caption='[[1dkw]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
===CRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1dkw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DKW FirstGlance]. <br>
{{ABSTRACT_PUBMED_11151009}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TBU:TERTIARY-BUTYL+ALCOHOL'>TBU</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dkw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dkw OCA], [https://pdbe.org/1dkw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dkw RCSB], [https://www.ebi.ac.uk/pdbsum/1dkw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dkw ProSAT]</span></td></tr>
[[1dkw]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKW OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPIS_TRYBB TPIS_TRYBB]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/1dkw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dkw ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[TIM test|TIM test]]
*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
__TOC__
 
</StructureSection>
==Reference==
[[Category: Large Structures]]
<ref group="xtra">PMID:011151009</ref><references group="xtra"/>
[[Category: Triose-phosphate isomerase]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Abagyan, R A.]]
[[Category: Abagyan RA]]
[[Category: Fernandez, A M.]]
[[Category: Fernandez AM]]
[[Category: Filimonov, V V.]]
[[Category: Filimonov VV]]
[[Category: Lambeir, A M.]]
[[Category: Lambeir AM]]
[[Category: Norledge, B V.]]
[[Category: Norledge BV]]
[[Category: Peter, M G.]]
[[Category: Peter MG]]
[[Category: Rottman, A.]]
[[Category: Rottman A]]
[[Category: Wierenga, R K.]]
[[Category: Wierenga RK]]
[[Category: Isomerase]]
[[Category: Modified loop-8]]
[[Category: Tim barrel]]

Latest revision as of 09:55, 7 February 2024

CRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITECRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITE

Structural highlights

1dkw is a 2 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.65Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TPIS_TRYBB

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1dkw, resolution 2.65Å

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OCA
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