1dkt: Difference between revisions

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{{Seed}}
[[Image:1dkt.png|left|200px]]


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==CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 COMPLEX WITH METAVANADATE==
The line below this paragraph, containing "STRUCTURE_1dkt", creates the "Structure Box" on the page.
<StructureSection load='1dkt' size='340' side='right'caption='[[1dkt]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1dkt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DKT FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=V7O:META+VANADATE'>V7O</scene></td></tr>
{{STRUCTURE_1dkt| PDB=1dkt |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dkt OCA], [https://pdbe.org/1dkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dkt RCSB], [https://www.ebi.ac.uk/pdbsum/1dkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dkt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CKS1_HUMAN CKS1_HUMAN] Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/1dkt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dkt ConSurf].
<div style="clear:both"></div>


===CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 COMPLEX WITH METAVANADATE===
==See Also==
 
*[[Cyclin-dependent kinase 3D structures|Cyclin-dependent kinase 3D structures]]
 
*[[Cyclin-dependent kinase regulatory subunit 3D structures|Cyclin-dependent kinase regulatory subunit 3D structures]]
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The line below this paragraph, {{ABSTRACT_PUBMED_7791211}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 7791211 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7791211}}
 
==About this Structure==
1DKT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKT OCA].
 
==Reference==
<ref group="xtra">PMID:7791211</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arvai, A S.]]
[[Category: Large Structures]]
[[Category: Bourne, Y.]]
[[Category: Arvai AS]]
[[Category: Tainer, J A.]]
[[Category: Bourne Y]]
[[Category: Cell division]]
[[Category: Tainer JA]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:13:22 2009''

Latest revision as of 09:55, 7 February 2024

CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 COMPLEX WITH METAVANADATECKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 COMPLEX WITH METAVANADATE

Structural highlights

1dkt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CKS1_HUMAN Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1dkt, resolution 2.90Å

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