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[[Image:1dc0.gif|left|200px]]


{{Structure
==CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG==
|PDB= 1dc0 |SIZE=350|CAPTION= <scene name='initialview01'>1dc0</scene>, resolution 1.3&Aring;
<StructureSection load='1dc0' size='340' side='right'caption='[[1dc0]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1dc0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DC0 FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
|GENE=
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dc0 OCA], [https://pdbe.org/1dc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dc0 RCSB], [https://www.ebi.ac.uk/pdbsum/1dc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dc0 ProSAT]</span></td></tr>
}}
</table>
 
__TOC__
'''CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG'''
</StructureSection>
 
[[Category: Large Structures]]
 
[[Category: Dickerson RE]]
==Overview==
[[Category: Kopka ML]]
The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A &lt;--&gt; B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition.
[[Category: Ng HL]]
 
==About this Structure==
1DC0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC0 OCA].  
 
==Reference==
The structure of a stable intermediate in the A &lt;--&gt; B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10688897 10688897]
[[Category: Protein complex]]
[[Category: Dickerson, R E.]]
[[Category: Kopka, M L.]]
[[Category: Ng, H. L.]]
[[Category: a-dna]]
[[Category: b-dna]]
[[Category: intermediate]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:36:02 2008''

Latest revision as of 09:51, 7 February 2024

CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATGCRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG

Structural highlights

1dc0 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

1dc0, resolution 1.30Å

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