1d8i: Difference between revisions

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[[Image:1d8i.png|left|200px]]


{{STRUCTURE_1d8i|  PDB=1d8i  |  SCENE=  }}
==X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION.==
 
<StructureSection load='1d8i' size='340' side='right'caption='[[1d8i]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
===X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1d8i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D8I FirstGlance]. <br>
{{ABSTRACT_PUBMED_10589681}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d8i OCA], [https://pdbe.org/1d8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d8i RCSB], [https://www.ebi.ac.uk/pdbsum/1d8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d8i ProSAT]</span></td></tr>
[[1d8i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D8I OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/CET1_YEAST CET1_YEAST] First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.<ref>PMID:12788946</ref>  
<ref group="xtra">PMID:010589681</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Polynucleotide 5'-phosphatase]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/1d8i_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d8i ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Lima, C D.]]
[[Category: Lima CD]]
[[Category: Shuman, S.]]
[[Category: Shuman S]]
[[Category: Wang, L K.]]
[[Category: Wang LK]]
[[Category: Beta subunit]]
[[Category: Catalytic domain]]
[[Category: Dimer]]
[[Category: Hydrolase]]
[[Category: Mrna capping]]
[[Category: Mrna processing]]
[[Category: Nuclear protein beta barrel]]
[[Category: Polynucleotide 5'-triphosphatase]]
[[Category: Rna triphosphatase]]
[[Category: Sulfate complex]]

Latest revision as of 09:50, 7 February 2024

X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION.X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION.

Structural highlights

1d8i is a 3 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CET1_YEAST First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Hausmann S, Pei Y, Shuman S. Homodimeric quaternary structure is required for the in vivo function and thermal stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA triphosphatases. J Biol Chem. 2003 Aug 15;278(33):30487-96. Epub 2003 Jun 3. PMID:12788946 doi:http://dx.doi.org/10.1074/jbc.M303060200

1d8i, resolution 2.05Å

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