1d1m: Difference between revisions

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[[Image:1d1m.png|left|200px]]


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==CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT==
The line below this paragraph, containing "STRUCTURE_1d1m", creates the "Structure Box" on the page.
<StructureSection load='1d1m' size='340' side='right'caption='[[1d1m]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1d1m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D1M FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d1m OCA], [https://pdbe.org/1d1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d1m RCSB], [https://www.ebi.ac.uk/pdbsum/1d1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d1m ProSAT]</span></td></tr>
{{STRUCTURE_1d1m|  PDB=1d1m  |  SCENE=  }}
</table>
 
== Function ==
===CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT===
[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d1m ConSurf].
1D1M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D1M OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
The structural basis for enhanced stability and reduced DNA binding seen in engineered second-generation Cro monomers and dimers., Rupert PB, Mollah AK, Mossing MC, Matthews BW, J Mol Biol. 2000 Mar 3;296(4):1079-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10686105 10686105]
[[Category: Escherichia virus Lambda]]
[[Category: Enterobacteria phage lambda]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Matthews BW]]
[[Category: Matthews, B W.]]
[[Category: Mollah AK]]
[[Category: Mollah, A K.]]
[[Category: Mossing MC]]
[[Category: Mossing, M C.]]
[[Category: Rupert PB]]
[[Category: Rupert, P B.]]
[[Category: Helix-turn-helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 22:05:38 2008''

Latest revision as of 09:47, 7 February 2024

CRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANTCRYSTAL STRUCTURE OF CRO K56-[DGEVK]-F58W MUTANT

Structural highlights

1d1m is a 2 chain structure with sequence from Escherichia virus Lambda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.05Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RCRO_LAMBD Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1d1m, resolution 2.05Å

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