1cxv: Difference between revisions

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-[[Image:1cxv.png|left|200px]]
-{{STRUCTURE_1cxv|  PDB=1cxv  |  SCENE=  }}
+==STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)==
+<StructureSection load='1cxv' size='340' side='right'caption='[[1cxv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===STRUCTURE OF RECOMBINANT MOUSE COLLAGENASE-3 (MMP-13)===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1cxv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CXV FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10525409}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CBP:2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE'>CBP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cxv OCA], [https://pdbe.org/1cxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cxv RCSB], [https://www.ebi.ac.uk/pdbsum/1cxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cxv ProSAT]</span></td></tr>
-[[1cxv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CXV OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MMP13_MOUSE MMP13_MOUSE] Degrades collagen type I.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/1cxv_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cxv ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Matrix metalloproteinase|Matrix metalloproteinase]]
+*[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:010525409</ref><references group="xtra"/>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Botos, I.]]
+[[Category: Botos I]]
-[[Category: Eeckhout, Y.]]
+[[Category: Eeckhout Y]]
-[[Category: Lemaitre, V.]]
+[[Category: Lemaitre V]]
-[[Category: Meyer, E.]]
+[[Category: Meyer E]]
-[[Category: Meyer, E F.]]
+[[Category: Meyer EF]]
-[[Category: Swanson, S M.]]
+[[Category: Swanson SM]]
-[[Category: Collagen degradation]]
-[[Category: Glycoprotein]]
-[[Category: Hydrolase]]
-[[Category: Metalloprotease]]