1cu0: Difference between revisions

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-{{Seed}}
-[[Image:1cu0.png|left|200px]]
-<!--
+==T4 LYSOZYME MUTANT I78M==
-The line below this paragraph, containing "STRUCTURE_1cu0", creates the "Structure Box" on the page.
+<StructureSection load='1cu0' size='340' side='right'caption='[[1cu0]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1cu0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CU0 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
-{{STRUCTURE_1cu0|  PDB=1cu0  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cu0 OCA], [https://pdbe.org/1cu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1cu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cu0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/1cu0_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cu0 ConSurf].
+<div style="clear:both"></div>
-===T4 LYSOZYME MUTANT I78M===
+==See Also==
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_10545167}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 10545167 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Escherichia virus T4]]
-{{ABSTRACT_PUBMED_10545167}}
+[[Category: Large Structures]]
+[[Category: Baase WA]]
-==About this Structure==
+[[Category: Gassner NC]]
-CU0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CU0 OCA].
+[[Category: Lindstrom JD]]
+[[Category: Lu J]]
-==Reference==
+[[Category: Matthews BW]]
-<ref group="xtra">PMID:10545167</ref><references group="xtra"/>
-[[Category: Enterobacteria phage t4]]
-[[Category: Lysozyme]]
-[[Category: Baase, W A.]]
-[[Category: Gassner, N C.]]
-[[Category: Lindstrom, J D.]]
-[[Category: Lu, J.]]
-[[Category: Matthews, B W.]]
-[[Category: Methionine core mutant]]
-[[Category: Protein engineering]]
-[[Category: Protein folding]]
-[[Category: T4 lysozyme]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:19:07 2009''