1csi: Difference between revisions

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{{Seed}}
[[Image:1csi.png|left|200px]]


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==A very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthase==
The line below this paragraph, containing "STRUCTURE_1csi", creates the "Structure Box" on the page.
<StructureSection load='1csi' size='340' side='right'caption='[[1csi]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1csi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CSI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMX:CARBOXYMETHYLDETHIA+COENZYME+*A'>CMX</scene>, <scene name='pdbligand=OAA:OXALOACETATE+ION'>OAA</scene></td></tr>
{{STRUCTURE_1csi|  PDB=1csi |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1csi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1csi OCA], [https://pdbe.org/1csi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1csi RCSB], [https://www.ebi.ac.uk/pdbsum/1csi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1csi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CISY_CHICK CISY_CHICK]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/1csi_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1csi ConSurf].
<div style="clear:both"></div>


===A VERY SHORT HYDROGEN BOND PROVIDES ONLY MODERATE STABILIZATION OF AN ENZYME: INHIBITOR COMPLEX OF CITRATE SYNTHASE===
==See Also==
 
*[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]]
 
__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 8011640 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8011640}}
 
==About this Structure==
1CSI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CSI OCA].
 
==Reference==
A very short hydrogen bond provides only moderate stabilization of an enzyme-inhibitor complex of citrate synthase., Usher KC, Remington SJ, Martin DP, Drueckhammer DG, Biochemistry. 1994 Jun 28;33(25):7753-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8011640 8011640]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Remington, S J.]]
[[Category: Remington SJ]]
[[Category: Usher, K C.]]
[[Category: Usher KC]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 21:17:10 2008''

Latest revision as of 09:45, 7 February 2024

A very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthaseA very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthase

Structural highlights

1csi is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CISY_CHICK

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1csi, resolution 1.70Å

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