1crk: Difference between revisions

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-[[Image:1crk.png|left|200px]]
-{{STRUCTURE_1crk|  PDB=1crk  |  SCENE=  }}
+==MITOCHONDRIAL CREATINE KINASE==
+<StructureSection load='1crk' size='340' side='right'caption='[[1crk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-===MITOCHONDRIAL CREATINE KINASE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1crk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CRK FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8692275}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1crk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1crk OCA], [https://pdbe.org/1crk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1crk RCSB], [https://www.ebi.ac.uk/pdbsum/1crk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1crk ProSAT]</span></td></tr>
-[[1crk]] is a 4 chain structure of [[Creatine Kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CRK OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KCRS_CHICK KCRS_CHICK] Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cr/1crk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1crk ConSurf].
+<div style="clear:both"></div>
 ==See Also==
 *[[Creatine Kinase|Creatine Kinase]]
+*[[Creatine kinase 3D structures|Creatine kinase 3D structures]]
-==Reference==
+__TOC__
-<ref group="xtra">PMID:008692275</ref><references group="xtra"/>
+</StructureSection>
-[[Category: Creatine kinase]]
 [[Category: Gallus gallus]]
-[[Category: Fritz-Wolf, K.]]
+[[Category: Large Structures]]
-[[Category: Kabsch, W.]]
+[[Category: Fritz-Wolf K]]
-[[Category: Schnyder, T.]]
+[[Category: Kabsch W]]
-[[Category: Wallimann, T.]]
+[[Category: Schnyder T]]
-[[Category: Creatine kinase]]
+[[Category: Wallimann T]]
-[[Category: Transferase]]