1c96: Difference between revisions

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-{{Seed}}
-[[Image:1c96.png|left|200px]]
-<!--
+==S642A:CITRATE COMPLEX OF ACONITASE==
-The line below this paragraph, containing "STRUCTURE_1c96", creates the "Structure Box" on the page.
+<StructureSection load='1c96' size='340' side='right'caption='[[1c96]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1c96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The May 2007 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aconitase and Iron Regulatory Protein 1''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2007_5 10.2210/rcsb_pdb/mom_2007_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C96 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=O:OXYGEN+ATOM'>O</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-{{STRUCTURE_1c96|  PDB=1c96  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c96 OCA], [https://pdbe.org/1c96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c96 RCSB], [https://www.ebi.ac.uk/pdbsum/1c96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c96 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ACON_BOVIN ACON_BOVIN] Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/1c96_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c96 ConSurf].
+<div style="clear:both"></div>
-===S642A:CITRATE COMPLEX OF ACONITASE===
+==See Also==
+*[[Aconitase 3D structures|Aconitase 3D structures]]
+__TOC__
-<!--
+</StructureSection>
-The line below this paragraph, {{ABSTRACT_PUBMED_10631981}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 10631981 is the PubMed ID number.
--->
-{{ABSTRACT_PUBMED_10631981}}
-==About this Structure==
-C96 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Additional information on 1C96 is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb89_1.html Aconitase and Iron Regulatory Protein 1] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C96 OCA].
-==Reference==
-The mechanism of aconitase: 1.8 A resolution crystal structure of the S642a:citrate complex., Lloyd SJ, Lauble H, Prasad GS, Stout CD, Protein Sci. 1999 Dec;8(12):2655-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10631981 10631981]
 [[Category: Aconitase and Iron Regulatory Protein 1]]
-[[Category: Aconitate hydratase]]
 [[Category: Bos taurus]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Lauble, H.]]
+[[Category: RCSB PDB Molecule of the Month]]
-[[Category: Lloyd, S J.]]
+[[Category: Lauble H]]
-[[Category: Prasad, G S.]]
+[[Category: Lloyd SJ]]
-[[Category: Stout, C D.]]
+[[Category: Prasad GS]]
-[[Category: 3d-structure]]
+[[Category: Stout CD]]
-[[Category: 4fe-4]]
-[[Category: Iron-sulfur]]
-[[Category: Lyase]]
-[[Category: Mitochondrion]]
-[[Category: Transit peptide]]
-[[Category: Tricarboxylic acid cycle]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 11:12:01 2008''