1c3r: Difference between revisions

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[[Image:1c3r.png|left|200px]]


{{STRUCTURE_1c3r|  PDB=1c3r  |  SCENE=  }}
==CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A==
 
<StructureSection load='1c3r' size='340' side='right'caption='[[1c3r]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1c3r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C3R FirstGlance]. <br>
{{ABSTRACT_PUBMED_10490031}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TSN:TRICHOSTATIN+A'>TSN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c3r OCA], [https://pdbe.org/1c3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c3r RCSB], [https://www.ebi.ac.uk/pdbsum/1c3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c3r ProSAT]</span></td></tr>
[[1c3r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3R OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/O67135_AQUAE O67135_AQUAE]
<ref group="xtra">PMID:010490031</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c3/1c3r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c3r ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Donigian, J R.]]
[[Category: Large Structures]]
[[Category: Finnin, M S.]]
[[Category: Donigian JR]]
[[Category: Pavletich, N P.]]
[[Category: Finnin MS]]
[[Category: Alpha/beta fold]]
[[Category: Pavletich NP]]
[[Category: Charge-relay system]]
[[Category: Hydroxamic acid]]
[[Category: Lyase]]
[[Category: Penta-coordinated zinc]]

Latest revision as of 09:41, 7 February 2024

CRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN ACRYSTAL STRUCTURE OF AN HDAC HOMOLOG COMPLEXED WITH TRICHOSTATIN A

Structural highlights

1c3r is a 2 chain structure with sequence from Aquifex aeolicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O67135_AQUAE

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1c3r, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA