1bsg: Difference between revisions

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-[[Image:1bsg.gif|left|200px]]<br /><applet load="1bsg" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="1bsg, resolution 1.85&Aring;" />
-'''BETA-LACTAMASE FROM STREPTOMYCES ALBUS G'''<br />
-==Overview==
+==BETA-LACTAMASE FROM STREPTOMYCES ALBUS G==
-The crystal structure of the beta-lactamase of Streptomyces albus G has been solved at 0.3 nm resolution by X-ray-diffraction methods. The enzyme is a typical two-domain protein. One domain consists of five alpha-helices, and the other is five-stranded beta-sheet with alpha-helices on both sides of the sheet. The active-site serine residue (Ser-48) is within a cleft located between the two domains.
+<StructureSection load='1bsg' size='340' side='right'caption='[[1bsg]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1bsg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_albus_G Streptomyces albus G]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BSG FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bsg OCA], [https://pdbe.org/1bsg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bsg RCSB], [https://www.ebi.ac.uk/pdbsum/1bsg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bsg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BLAC_STRAL BLAC_STRAL]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/1bsg_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bsg ConSurf].
+<div style="clear:both"></div>
-==About this Structure==
+==See Also==
-BSG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_albus_g Streptomyces albus g] with <scene name='pdbligand=ACT:'>ACT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BSG OCA].
+*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution., Dideberg O, Charlier P, Wery JP, Dehottay P, Dusart J, Erpicum T, Frere JM, Ghuysen JM, Biochem J. 1987 Aug 1;245(3):911-3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3499147 3499147]
+[[Category: Large Structures]]
-[[Category: Beta-lactamase]]
+[[Category: Streptomyces albus G]]
-[[Category: Single protein]]
+[[Category: Charlier P]]
-[[Category: Streptomyces albus g]]
+[[Category: Dideberg O]]
-[[Category: Charlier, P.]]
+[[Category: Fonze E]]
-[[Category: Dideberg, O.]]
-[[Category: Fonze, E.]]
-[[Category: ACT]]
-[[Category: antibiotic resistance]]
-[[Category: hydrolase]]
-[[Category: penicillin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:58:36 2008''