1brk: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1brk.png|left|200px]]
-{{STRUCTURE_1brk|  PDB=1brk  |  SCENE=  }}
+==BARNASE MUTANT WITH ILE 96 REPLACED BY ALA==
+<StructureSection load='1brk' size='340' side='right'caption='[[1brk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===BARNASE MUTANT WITH ILE 96 REPLACED BY ALA===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1brk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRK FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8605178}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1brk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brk OCA], [https://pdbe.org/1brk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1brk RCSB], [https://www.ebi.ac.uk/pdbsum/1brk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1brk ProSAT]</span></td></tr>
-[[1brk]] is a 3 chain structure of [[Barnase]] and [[Ribonuclease]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRK OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RNBR_BACAM RNBR_BACAM] Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1brk_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1brk ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Barnase|Barnase]]
+*[[Barnase 3D structures|Barnase 3D structures]]
-*[[Ribonuclease|Ribonuclease]]
+*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:008605178</ref><references group="xtra"/>
 [[Category: Bacillus amyloliquefaciens]]
-[[Category: Buckle, A.]]
+[[Category: Large Structures]]
-[[Category: Cramer, P C.]]
+[[Category: Buckle A]]
-[[Category: Fersht, A.]]
+[[Category: Cramer PC]]
-[[Category: Alpha/beta protein]]
+[[Category: Fersht A]]
-[[Category: Endonuclease]]