1bmf: Difference between revisions

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-[[Image:1bmf.png|left|200px]]
-{{STRUCTURE_1bmf|  PDB=1bmf  |  SCENE=  }}
+==BOVINE MITOCHONDRIAL F1-ATPASE==
+<StructureSection load='1bmf' size='340' side='right'caption='[[1bmf]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
-===BOVINE MITOCHONDRIAL F1-ATPASE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1bmf]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BMF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BMF FirstGlance]. <br>
-{{ABSTRACT_PUBMED_8065448}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bmf OCA], [https://pdbe.org/1bmf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bmf RCSB], [https://www.ebi.ac.uk/pdbsum/1bmf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bmf ProSAT]</span></td></tr>
-[[1bmf]] is a 7 chain structure of [[ATP synthase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BMF OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/ATPA_BOVIN ATPA_BOVIN] Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bm/1bmf_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bmf ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[ATP synthase|ATP synthase]]
+*[[ATPase 3D structures|ATPase 3D structures]]
-*[[Nobel Prizes for 3D Molecular Structure|Nobel Prizes for 3D Molecular Structure]]
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:008065448</ref><references group="xtra"/>
 [[Category: Bos taurus]]
-[[Category: Abrahams, J P.]]
+[[Category: Large Structures]]
-[[Category: Leslie, A G.W.]]
+[[Category: Abrahams JP]]
-[[Category: Lutter, R.]]
+[[Category: Leslie AGW]]
-[[Category: Walker, J E.]]
+[[Category: Lutter R]]
-[[Category: Atp phosphorylase]]
+[[Category: Walker JE]]
-[[Category: Atp synthase]]
-[[Category: F1-atpase]]
-[[Category: F1fo atp synthase]]