1bk5: Difference between revisions

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-{{Seed}}
-[[Image:1bk5.png|left|200px]]
-<!--
+==KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE==
-The line below this paragraph, containing "STRUCTURE_1bk5", creates the "Structure Box" on the page.
+<StructureSection load='1bk5' size='340' side='right'caption='[[1bk5]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1bk5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BK5 FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
-{{STRUCTURE_1bk5|  PDB=1bk5  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bk5 OCA], [https://pdbe.org/1bk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bk5 RCSB], [https://www.ebi.ac.uk/pdbsum/1bk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bk5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IMA1_YEAST IMA1_YEAST] Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity).<ref>PMID:7565597</ref> <ref>PMID:10913188</ref> <ref>PMID:21075847</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/1bk5_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bk5 ConSurf].
+<div style="clear:both"></div>
-===KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE===
+==See Also==
+*[[Importin 3D structures|Importin 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_9695948}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 9695948 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Large Structures]]
-{{ABSTRACT_PUBMED_9695948}}
-==About this Structure==
-BK5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BK5 OCA].
-==Reference==
-<ref group="xtra">PMID:9695948</ref><references group="xtra"/>
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Blobel, G.]]
+[[Category: Blobel G]]
-[[Category: Conti, E.]]
+[[Category: Conti E]]
-[[Category: Kuriyan, J.]]
+[[Category: Kuriyan J]]
-[[Category: Leighton, L.]]
+[[Category: Leighton L]]
-[[Category: Uy, M.]]
+[[Category: Uy M]]
-[[Category: Armadillo repeat containing protein]]
-[[Category: Nls nuclear import]]
-[[Category: Protein transport]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:55:52 2009''