1bjt: Difference between revisions

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-[[Image:1bjt.png|left|200px]]
-{{STRUCTURE_1bjt|  PDB=1bjt  |  SCENE=  }}
+==TOPOISOMERASE II RESIDUES 409-1201==
+<StructureSection load='1bjt' size='340' side='right'caption='[[1bjt]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-===TOPOISOMERASE II RESIDUES 409-1201===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1bjt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BJT FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10201398}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bjt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bjt OCA], [https://pdbe.org/1bjt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bjt RCSB], [https://www.ebi.ac.uk/pdbsum/1bjt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bjt ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1bjt]] is a 1 chain structure of [[Topoisomerase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJT OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/TOP2_YEAST TOP2_YEAST] Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.<ref>PMID:9685374</ref> <ref>PMID:23022727</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/1bjt_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bjt ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Topoisomerase|Topoisomerase]]
+*[[Topoisomerase 3D structures|Topoisomerase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:010201398</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Berger, J M.]]
+[[Category: Berger JM]]
-[[Category: Bogden, C E.]]
+[[Category: Bogden CE]]
-[[Category: Fass, D.]]
+[[Category: Fass D]]
-[[Category: Dna topology]]
-[[Category: Dna-binding]]
-[[Category: Quaternary change]]
-[[Category: Topoisomerase]]