1bi2: Difference between revisions

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[[Image:1bi2.png|left|200px]]


{{STRUCTURE_1bi2| PDB=1bi2 | SCENE= }}
==STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR==
<StructureSection load='1bi2' size='340' side='right'caption='[[1bi2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1bi2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BI2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bi2 OCA], [https://pdbe.org/1bi2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bi2 RCSB], [https://www.ebi.ac.uk/pdbsum/1bi2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bi2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DTXR_CORDI DTXR_CORDI] Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bi/1bi2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bi2 ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR===
==See Also==
 
*[[Diphtheria toxin repressor|Diphtheria toxin repressor]]
{{ABSTRACT_PUBMED_9712865}}
__TOC__
 
</StructureSection>
==About this Structure==
[[1bi2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_diphtheriae Corynebacterium diphtheriae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BI2 OCA].
 
==Reference==
<ref group="xtra">PMID:009712865</ref><references group="xtra"/>
[[Category: Corynebacterium diphtheriae]]
[[Category: Corynebacterium diphtheriae]]
[[Category: Hol, W G.J.]]
[[Category: Large Structures]]
[[Category: Pohl, E.]]
[[Category: Hol WGJ]]
[[Category: Dna-binding]]
[[Category: Pohl E]]
[[Category: Iron]]
[[Category: Repressor]]
[[Category: Transcription regulation]]

Latest revision as of 09:36, 7 February 2024

STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSORSTRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR

Structural highlights

1bi2 is a 2 chain structure with sequence from Corynebacterium diphtheriae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DTXR_CORDI Iron-binding repressor of the dipheteria toxin gene expression. May serve as a global regulator of gene expression. Represses ripA under iron excess.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1bi2, resolution 2.30Å

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