1bcz: Difference between revisions

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[[Image:1bcz.png|left|200px]]


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==RECOMBINANT RAT ANNEXIN V, T72S MUTANT==
The line below this paragraph, containing "STRUCTURE_1bcz", creates the "Structure Box" on the page.
<StructureSection load='1bcz' size='340' side='right'caption='[[1bcz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1bcz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BCZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BCZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1bcz| PDB=1bcz |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bcz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bcz OCA], [https://pdbe.org/1bcz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bcz RCSB], [https://www.ebi.ac.uk/pdbsum/1bcz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bcz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ANXA5_RAT ANXA5_RAT] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/1bcz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bcz ConSurf].
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===RECOMBINANT RAT ANNEXIN V, T72S MUTANT===
==See Also==
 
*[[Annexin 3D structures|Annexin 3D structures]]
 
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_9609693}}
 
==About this Structure==
1BCZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BCZ OCA].
 
==Reference==
Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components., Campos B, Mo YD, Mealy TR, Li CW, Swairjo MA, Balch C, Head JF, Retzinger G, Dedman JR, Seaton BA, Biochemistry. 1998 Jun 2;37(22):8004-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9609693 9609693]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Head JF]]
[[Category: Head, J F.]]
[[Category: Li CW]]
[[Category: Li, C W.]]
[[Category: Mo YD]]
[[Category: Mo, Y D.]]
[[Category: Seaton BA]]
[[Category: Seaton, B A.]]
[[Category: Swairjo MA]]
[[Category: Swairjo, M A.]]
[[Category: Calcium binding protein]]
[[Category: Phospholipid membrane binding protein]]
 
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