1bc2: Difference between revisions

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-[[Image:1bc2.png|left|200px]]
-{{STRUCTURE_1bc2|  PDB=1bc2  |  SCENE=  }}
+==ZN-DEPENDENT METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS==
+<StructureSection load='1bc2' size='340' side='right'caption='[[1bc2]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===ZN-DEPENDENT METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1bc2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BC2 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_9730812}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bc2 OCA], [https://pdbe.org/1bc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bc2 RCSB], [https://www.ebi.ac.uk/pdbsum/1bc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bc2 ProSAT]</span></td></tr>
-[[1bc2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BC2 OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bc/1bc2_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bc2 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Beta-lactamase|Beta-lactamase]]
+*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:009730812</ref><ref group="xtra">PMID:010708646</ref><references group="xtra"/>
 [[Category: Bacillus cereus]]
-[[Category: Beta-lactamase]]
+[[Category: Large Structures]]
-[[Category: Fabiane, S M.]]
+[[Category: Fabiane SM]]
-[[Category: Sutton, B J.]]
+[[Category: Sutton BJ]]
-[[Category: Antibiotic resistance]]
-[[Category: Hydrolase]]
-[[Category: Metallo beta-lactamase]]
-[[Category: Penicillinase]]