1atg: Difference between revisions

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-[[Image:1atg.gif|left|200px]]<br />
-<applet load="1atg" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="1atg, resolution 1.2&Aring;" />
-'''AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN'''<br />
-==Overview==
+==AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN==
-Background:. Periplasmic receptors constitute a diverse class of binding, proteins that differ widely in size, sequence and ligand specificity., Nevertheless, almost all of them display a common beta/alpha folding motif, and have similar tertiary structures consisting of two globular domains., The ligand is bound at the bottom of a deep cleft, which lies at the, interface between these two domains. The oxyanion-binding proteins are, notable in that they can discriminate between very similar ligands., Results:. Azotobacter vinelandii is unusual in that it possesses two, periplasmic molybdate-binding proteins. The crystal structure of one of, these with bound ligand has been determined at 1.2 A resolution. It, superficially resembles the structure of sulphate-binding protein (SBP), from ... [[http://ispc.weizmann.ac.il/pmbin/getpm?9862806 (full description)]]
+<StructureSection load='1atg' size='340' side='right'caption='[[1atg]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1atg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ATG FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1atg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atg OCA], [https://pdbe.org/1atg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1atg RCSB], [https://www.ebi.ac.uk/pdbsum/1atg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1atg ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q7SIH2_AZOVI Q7SIH2_AZOVI]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/1atg_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1atg ConSurf].
+<div style="clear:both"></div>
-==About this Structure==
+==See Also==
-ATG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]] with WO4, ACT, SO4 and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: MOB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ATG OCA]].
+*[[ABC transporter 3D structures|ABC transporter 3D structures]]
+*[[ModG|ModG]]
-==Reference==
+__TOC__
-Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA., Lawson DM, Williams CE, Mitchenall LA, Pau RN, Structure. 1998 Dec 15;6(12):1529-39. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9862806 9862806]
+</StructureSection>
 [[Category: Azotobacter vinelandii]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Lawson, D.M.]]
+[[Category: Lawson DM]]
-[[Category: Mitchenall, L.A.]]
+[[Category: Mitchenall LA]]
-[[Category: Pau, R.N.]]
+[[Category: Pau RN]]
-[[Category: Williams, C.E.M.]]
+[[Category: Williams CEM]]
-[[Category: ACT]]
-[[Category: EDO]]
-[[Category: SO4]]
-[[Category: WO4]]
-[[Category: abc transporter]]
-[[Category: binding protein]]
-[[Category: molybdate]]
-[[Category: periplasm]]
-[[Category: tungstate]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:59:14 2007''