1ae9: Difference between revisions

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-[[Image:1ae9.png|left|200px]]
-{{STRUCTURE_1ae9|  PDB=1ae9  |  SCENE=  }}
+==STRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORE==
+<StructureSection load='1ae9' size='340' side='right'caption='[[1ae9]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-===STRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1ae9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AE9 FirstGlance]. <br>
-{{ABSTRACT_PUBMED_9082984}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ae9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ae9 OCA], [https://pdbe.org/1ae9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ae9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ae9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ae9 ProSAT]</span></td></tr>
-==About this Structure==
+</table>
-[[1ae9]] is a 2 chain structure of [[Phage integrase]] and [[Resolvase]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AE9 OCA].
+== Function ==
+[https://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/1ae9_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ae9 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Phage integrase|Phage integrase]]
+*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
-*[[Resolvase|Resolvase]]
+__TOC__
+</StructureSection>
-==Reference==
+[[Category: Escherichia virus Lambda]]
-<ref group="xtra">PMID:009082984</ref><references group="xtra"/>
+[[Category: Large Structures]]
-[[Category: Enterobacteria phage lambda]]
+[[Category: Ellenberger T]]
-[[Category: Ellenberger, T.]]
+[[Category: Kwon HJ]]
-[[Category: Kwon, H J.]]
+[[Category: Landy A]]
-[[Category: Landy, A.]]
+[[Category: Tirumalai R]]
-[[Category: Tirumalai, R.]]
-[[Category: Dna recombination]]
-[[Category: Integrase]]
-[[Category: Site-specific recombination]]