1ae9: Difference between revisions
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==STRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORE== | |||
<StructureSection load='1ae9' size='340' side='right'caption='[[1ae9]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1ae9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AE9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ae9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ae9 OCA], [https://pdbe.org/1ae9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ae9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ae9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ae9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
< | Check<jmol> | ||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/1ae9_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
== | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ae9 ConSurf]. | ||
[[1ae9]] is a 2 chain structure | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[ | *[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia virus Lambda]] | |||
[[Category: Large Structures]] | |||
[[Category: | [[Category: Ellenberger T]] | ||
[[Category: Ellenberger | [[Category: Kwon HJ]] | ||
[[Category: Kwon | [[Category: Landy A]] | ||
[[Category: Landy | [[Category: Tirumalai R]] | ||
[[Category: Tirumalai | |||
Latest revision as of 09:30, 7 February 2024
STRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORESTRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORE
Structural highlights
FunctionVINT_LAMBD Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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