1a8v: Difference between revisions

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-[[Image:1a8v.png|left|200px]]
-{{STRUCTURE_1a8v|  PDB=1a8v  |  SCENE=  }}
+==STRUCTURE OF THE RNA-BINDING DOMAIN OF THE RHO TRANSCRIPTION TERMINATOR==
+<StructureSection load='1a8v' size='340' side='right'caption='[[1a8v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-===STRUCTURE OF THE RNA-BINDING DOMAIN OF THE RHO TRANSCRIPTION TERMINATOR===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1a8v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A8V FirstGlance]. <br>
-{{ABSTRACT_PUBMED_10230401}}
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a8v OCA], [https://pdbe.org/1a8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a8v RCSB], [https://www.ebi.ac.uk/pdbsum/1a8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a8v ProSAT]</span></td></tr>
-[[1a8v]] is a 2 chain structure of [[Helicase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A8V OCA].
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RHO_ECOLI RHO_ECOLI] Facilitates transcription termination by a mechanism that involves rho binding to the nascent RNA, activation of rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPAse which utilizes all four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01884]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a8/1a8v_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a8v ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Helicase|Helicase]]
+*[[Helicase 3D structures|Helicase 3D structures]]
-*[[Transcription Termination Factor Rho|Transcription Termination Factor Rho]]
+__TOC__
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:010230401</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
 [[Category: Escherichia coli]]
-[[Category: Berger, J M.]]
+[[Category: Large Structures]]
-[[Category: Bogden, C.]]
+[[Category: Berger JM]]
-[[Category: Fass, D.]]
+[[Category: Bogden C]]
-[[Category: Rho protein]]
+[[Category: Fass D]]
-[[Category: Rna-binding]]
-[[Category: Terminator]]
-[[Category: Transcription termination]]