2yla: Difference between revisions

No edit summary
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:


==Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis==
==INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS==
<StructureSection load='2yla' size='340' side='right' caption='[[2yla]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2yla' size='340' side='right'caption='[[2yla]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yla]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YLA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yla]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YLA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yl8|2yl8]], [[2yl9|2yl9]], [[2yl6|2yl6]], [[2yl5|2yl5]], [[2yll|2yll]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yla OCA], [https://pdbe.org/2yla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yla RCSB], [https://www.ebi.ac.uk/pdbsum/2yla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yla ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yla OCA], [http://pdbe.org/2yla PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yla RCSB], [http://www.ebi.ac.uk/pdbsum/2yla PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yla ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/STRH_STRPN STRH_STRPN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 22:
==See Also==
==See Also==
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-N-acetylhexosaminidase]]
[[Category: Large Structures]]
[[Category: Strpn]]
[[Category: Streptococcus pneumoniae TIGR4]]
[[Category: Abbott, D W]]
[[Category: Abbott DW]]
[[Category: Boraston, A B]]
[[Category: Boraston AB]]
[[Category: Dalia, A B]]
[[Category: Dalia AB]]
[[Category: Deng, L]]
[[Category: Deng L]]
[[Category: Fairbanks, A J]]
[[Category: Fairbanks AJ]]
[[Category: Higgins, M A]]
[[Category: Higgins MA]]
[[Category: Parsons, T B]]
[[Category: Parsons TB]]
[[Category: Pluvinage, B]]
[[Category: Pluvinage B]]
[[Category: Robb, C]]
[[Category: Robb C]]
[[Category: Vocadlo, D J]]
[[Category: Vocadlo DJ]]
[[Category: Weiser, J N]]
[[Category: Weiser JN]]
[[Category: Hydrolase]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA