2y9y: Difference between revisions
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==Chromatin Remodeling Factor ISW1a(del_ATPase)== | ==Chromatin Remodeling Factor ISW1a(del_ATPase)== | ||
<StructureSection load='2y9y' size='340' side='right' caption='[[2y9y]], [[Resolution|resolution]] 3.25Å' scene=''> | <StructureSection load='2y9y' size='340' side='right'caption='[[2y9y]], [[Resolution|resolution]] 3.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2y9y]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2y9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y9Y FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25Å</td></tr> | ||
<tr | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y9y OCA], [https://pdbe.org/2y9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y9y RCSB], [https://www.ebi.ac.uk/pdbsum/2y9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y9y ProSAT]</span></td></tr> | ||
</table> | |||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/ISW1_YEAST ISW1_YEAST] Catalytic component of ISW1-type complexes, which act by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. They are involved in coordinating transcriptional repression, activation and elongation phases. The ISW1A complex represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome. The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing.<ref>PMID:10090725</ref> <ref>PMID:11238381</ref> <ref>PMID:14622597</ref> <ref>PMID:12482963</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structure and mechanism of the chromatin remodelling factor ISW1a.,Yamada K, Frouws TD, Angst B, Fitzgerald DJ, DeLuca C, Schimmele K, Sargent DF, Richmond TJ Nature. 2011 Apr 28;472(7344):448-53. PMID:21525927<ref>PMID:21525927</ref> | Structure and mechanism of the chromatin remodelling factor ISW1a.,Yamada K, Frouws TD, Angst B, Fitzgerald DJ, DeLuca C, Schimmele K, Sargent DF, Richmond TJ Nature. 2011 Apr 28;472(7344):448-53. PMID:21525927<ref>PMID:21525927</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2y9y" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Angst | [[Category: Angst B]] | ||
[[Category: | [[Category: DeLuca C]] | ||
[[Category: Fitzgerald | [[Category: Fitzgerald DJ]] | ||
[[Category: Frouws | [[Category: Frouws TD]] | ||
[[Category: Richmond | [[Category: Richmond TJ]] | ||
[[Category: Sargent | [[Category: Sargent DF]] | ||
[[Category: Schimmele | [[Category: Schimmele K]] | ||
[[Category: Yamada | [[Category: Yamada K]] | ||