7ocb: Difference between revisions
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New page: '''Unreleased structure''' The entry 7ocb is ON HOLD Authors: Johansson, C., Krojer, T., Park, K., Xiong, Y., Jin, J., Oppermann, U. Description: Crystal structure of Spindlin1 in comp... |
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==Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B== | |||
<StructureSection load='7ocb' size='340' side='right'caption='[[7ocb]], [[Resolution|resolution]] 1.42Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7ocb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OCB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=V88:7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine'>V88</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ocb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ocb OCA], [https://pdbe.org/7ocb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ocb RCSB], [https://www.ebi.ac.uk/pdbsum/7ocb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ocb ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). | |||
==See Also== | |||
*[[Spindlin|Spindlin]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Jin J]] | ||
[[Category: | [[Category: Johansson C]] | ||
[[Category: | [[Category: Krojer T]] | ||
[[Category: | [[Category: Oppermann U]] | ||
[[Category: Park K]] | |||
[[Category: Xiong Y]] | |||
Latest revision as of 15:48, 1 February 2024
Crystal structure of Spindlin1 in complex with the inhibitor XY49-92BCrystal structure of Spindlin1 in complex with the inhibitor XY49-92B
Structural highlights
FunctionSPIN1_HUMAN May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). See Also |
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