Tryptophan synthase 3D structures: Difference between revisions
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Michal Harel (talk | contribs) New page: ==3D structures of tryptophan synthase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Tryptophan synthase α... |
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==3D structures of tryptophan synthase== | ==3D structures of tryptophan synthase== | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Tryptophan synthase]] | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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**[[5kmy]], [[5k9x]], [[6oky]] - TrpS α subunit – ''Legionella pneumophila''<br /> | **[[5kmy]], [[5k9x]], [[6oky]] - TrpS α subunit – ''Legionella pneumophila''<br /> | ||
**[[5n2p]] - SsTrpS α subunit – ''Sulfolobus solfataricus''<br /> | **[[5n2p]] - SsTrpS α subunit – ''Sulfolobus solfataricus''<br /> | ||
**[[6oso]], [[6ouy]] - StTrpS α subunit – ''Salmonella typhimurium''<br /> | |||
**[[6qky]] - SpTrpS α subunit – ''Streptococcus pneumoniae''<br /> | |||
*Tryptophan synthase α binary complex | *Tryptophan synthase α binary complex | ||
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**[[2dh6]] - EcTrpS β subunit - ''Escherichia coli''<br /> | **[[2dh6]] - EcTrpS β subunit - ''Escherichia coli''<br /> | ||
**[[2o2e]], [[2o2j]] - MtTrpS β subunit – ''Mycobacterium tuberculosis''<br /> | **[[2o2e]], [[2o2j]] - MtTrpS β subunit – ''Mycobacterium tuberculosis''<br /> | ||
**[[1v8z]] - PfTrpS β1 subunit <br /> | **[[1v8z]], [[5vm5]], [[6am7]], [[6am9]], [[6amc]], [[6amh]], [[6cuv]] - PfTrpS β1 subunit <br /> | ||
**[[4neg]] - TrpS β subunit – ''Bacillus anthracis''<br /> | **[[4neg]] - TrpS β subunit – ''Bacillus anthracis''<br /> | ||
*Tryptophan synthase β complex | *Tryptophan synthase β complex | ||
**[[2dh5]] - EcTrpS β subunit + PLP<br /> | **[[2dh5]] - EcTrpS β subunit + PLP<br /> | ||
**[[ | **[[4qys]], [[6hte]] - SsTrpS β2 subunit + PLP<br /> | ||
**[[5dvz]] - PfTrpS β1 subunit + PLP derivative <br /> | **[[5dvz]] - PfTrpS β1 subunit + PLP derivative <br /> | ||
**[[6am7]], [[6amc]], [[6cuv]] - PfTrpS β1 subunit (mutant) + PLP derivative <br /> | **[[6am7]], [[6amc]], [[6cuv]], [[7rnq]] - PfTrpS β1 subunit (mutant) + PLP derivative <br /> | ||
**[[5dw0]] - PfTrpS β1 subunit + Ser derivative <br /> | **[[5dw0]] - PfTrpS β1 subunit + Ser derivative <br /> | ||
**[[5dw3]] - PfTrpS β1 subunit + PLP derivative + Trp<br /> | **[[5dw3]] - PfTrpS β1 subunit + PLP derivative + Trp<br /> | ||
**[[6am8]], [[6ami]] - PfTrpS β1 subunit (mutant) + PLP derivative + Trp<br /> | **[[6am8]], [[6ami]] - PfTrpS β1 subunit (mutant) + PLP derivative + Trp<br /> | ||
**[[5t6m]] - PfTrpS β1 subunit + PLP derivative + Trp derivative<br /> | **[[5t6m]] - PfTrpS β1 subunit + PLP derivative + Trp derivative<br /> | ||
**[[7rnp]], [[7rof]] - PfTrpS β1 subunit (mutant) + PLP derivative + Trp derivative<br /> | |||
**[[6xsy]] - PfTrpS β1 subunit (mutant) + PLP derivative + inhibitor<br /> | |||
**[[5vm5]] - PfTrpS β1 subunit + PLP derivative + Ser derivative<br /> | **[[5vm5]] - PfTrpS β1 subunit + PLP derivative + Ser derivative<br /> | ||
**[[5ixj]] - PfTrpS β1 subunit + PLP derivative + Thr<br /> | **[[5ixj]] - PfTrpS β1 subunit + PLP derivative + Thr<br /> | ||
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**[[6cut]] - PfTrpS β1 subunit (mutant) + Trp analog <br /> | **[[6cut]] - PfTrpS β1 subunit (mutant) + Trp analog <br /> | ||
**[[6cuz]] - PfTrpS β1 subunit (mutant) + PLP derivative + ethylserine<br /> | **[[6cuz]] - PfTrpS β1 subunit (mutant) + PLP derivative + ethylserine<br /> | ||
**[[8egy]], [[8egz]] - TmTrpS β1 subunit + PLP derivative – ''Thermotoga maritima''<br /> | |||
**[[8eh0]] - TmTrpS β1 subunit + PLP derivative + quinoline derivative<br /> | |||
*'''Tryptophan synthase α+β subunits''' | *'''Tryptophan synthase α+β subunits''' | ||
**[[1wdw]] - PfTrpS α + β subunits <br /> | **[[1wdw]] - PfTrpS α + β subunits <br /> | ||
**[[ | **[[5tcf]] - MtTrpS α + β <br /> | ||
**[[6wdu]], [[7a20]], [[7l5h]], [[7lev]] - StTrpS α + β <br /> | |||
**[[7kq9]] - StTrpS α + β (mutant)<br /> | |||
**[[6v82]] - TrpS α + β – ''Chlamydia trachomatis''<br /> | |||
*Tryptophan synthase α+β binary complex | *Tryptophan synthase α+β binary complex | ||
**[[1ttp]], [[1ttq]], [[1bks]], [[2wsy]], [[1kfk]] - StTrpS α + β + PLP | **[[1ttp]], [[1ttq]], [[1bks]], [[2wsy]], [[1kfk]], [[7l4d]], [[7lx1]], [[8b03]] - StTrpS α + β + PLP <br /> | ||
**[[1k7x]], [[2j9z]] - StTrpS α + β (mutant) + PLP<br /> | **[[6dz4]], [[8b05]], [[8b08]] - StTrpS α + β + PLP derivative<br /> | ||
**[[3pr2]], [[4hn4]], [[4hpj]], [[4hpx]], [[4ht3]], [[4kkx]] - StTrpS α + β + inhibitor<br /> | **[[1k7x]], [[2j9z]], [[7kmc]], [[7l47]] - StTrpS α + β (mutant) + PLP<br /> | ||
**[[3pr2]], [[4hn4]], [[4hpj]], [[4hpx]], [[4ht3]], [[4kkx]], [[7kwv]], [[7kxc]], [[7kyt]], [[7l03]] - StTrpS α + β + inhibitor<br /> | |||
**[[1kfj]] - StTrpS α + β + pyridoxal-serine-monophsphate<br /> | **[[1kfj]] - StTrpS α + β + pyridoxal-serine-monophsphate<br /> | ||
**[[1a5a]], [[1k8x]] - StTrpS α (mutant) + β + PLP<br /> | **[[1a5a]], [[1k8x]] - StTrpS α (mutant) + β + PLP<br /> | ||
**[[1kfe]] - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate<br /> | **[[1kfe]] - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate<br /> | ||
**[[6o1h]], [[6dzo]], [[6duc]], [[6d0v]], [[6c73]] - StTrpS α + β (mutant) + inhibitor<br /> | **[[7ku9]], [[7l1h]], [[7lgx]], [[7mt4]], [[7mt5]], [[7mt6]] - StTrpS α + β + inhibitor<br /> | ||
**[[2j9y]] - StTrpS α + β (mutant) + enoic acid derivative<br /> | **[[6o1h]], [[6dzo]], [[6duc]], [[6d0v]], [[6c73]], [[6x0c]], [[7jmq]], [[7kbn]], [[7ki7]] - StTrpS α + β (mutant) + inhibitor<br /> | ||
**[[2j9y]], [[7lt4]] - StTrpS α + β (mutant) + enoic acid derivative<br /> | |||
**[[6xrh]], [[6xt0]] - StTrpS α + β (mutant) + IGP + Ala derivative<br /> | |||
**[[7jqw]], [[7k5a]] - StTrpS α + β (mutant) + Ser <br /> | |||
**[[2tys]] - StTrpS α (mutant) + β (mutant) + Trp derivative<br /> | **[[2tys]] - StTrpS α (mutant) + β (mutant) + Trp derivative<br /> | ||
**[[5kzm]] - TrpS α + β + PLP derivative – ''Francisella tularensis''<br /> | **[[5kzm]] - TrpS α + β + PLP derivative – ''Francisella tularensis''<br /> | ||
**[[5kin]] - | **[[5kin]] - SpTrpS α + β + PLP derivative – ''Streptococcus pneumoniae''<br /> | ||
**[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | **[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | ||
**[[5ocw]], [[5tcg]], [[5tci]], [[5tcj]] - MtTrpS α + β + inhibitor<br /> | **[[5ocw]], [[5tcg]], [[5tci]], [[5tcj]] - MtTrpS α + β + inhibitor<br /> | ||
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**[[5tch]] - MtTrpS α + β (mutant) + PLP derivative <br /> | **[[5tch]] - MtTrpS α + β (mutant) + PLP derivative <br /> | ||
**[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | **[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | ||
**[[5ey5]] - TrpS α + β + PLP - synthetic <br /> | |||
*Tryptophan synthase α+β ternary complex with PLP and inhibitor | *Tryptophan synthase α+β ternary complex with PLP and inhibitor | ||
**[[1a50]], [[1cw2]], [[1c9d]], [[1cx9]], [[1c8v]], [[1c29]], [[2cle]], [[2clh]], [[2cli]], [[2clk]], [[2cll]], [[2clm]], [[2clo]], [[2clf]], [[5bw6]], [[4zqc]], [[4y6g]], [[4xug]], [[4wx2]], [[5bw6]] - StTrpS α + β + inhibitor + PLP<br /> | **[[1a50]], [[1cw2]], [[1c9d]], [[1cx9]], [[1c8v]], [[1c29]], [[2cle]], [[2clh]], [[2cli]], [[2clk]], [[2cll]], [[2clm]], [[2clo]], [[2clf]], [[5bw6]], [[4zqc]], [[4y6g]], [[4xug]], [[4wx2]], [[5bw6]], [[6vnt]], [[6wx3]], [[6xin]], [[7kqf]], [[7lpf]], [[7lvx]], [[7ly8]], [[7m2l]], [[7m3s]], [[7me8]] - StTrpS α + β + inhibitor + PLP<br /> | ||
**[[ | **[[1fuy]], [[7jhw]], [[7kh6]] - StTrpS α + β (mutant) + inhibitor + PLP<br /> | ||
**[[ | **[[6xe3]] - StTrpS α + β (mutant) + inhibitor + PLP derivative<br /> | ||
*Tryptophan synthase α+β ternary complex with PLP and IGP derivatives | *Tryptophan synthase α+β ternary complex with PLP and IGP derivatives | ||
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**[[2tsy]] - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + G3P | **[[2tsy]] - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + G3P | ||
**[[1ubs]] - StTrpS α (mutant) + β (mutant) + | *Other TrpS α+β ternary complex | ||
**[[6hul]] - SsTrpS α + β subunits + PLP + Ser<br /> | |||
**[[8b06]] - StTrpS α + β + Ser + PLP<br /> | |||
**[[7k0b]] - StTrpS α + β (mutant) + Ser + PLP<br /> | |||
**[[1ubs]] - StTrpS α (mutant) + β (mutant) + Ser + PLP<br /> | |||
**[[7jtt]], [[7ka1]] - StTrpS α + β (mutant) + Ser + inhibitor<br /> | |||
**[[6vfd]] - StTrpS α + β + quinoid derivative + Ser<br /> | |||
**[[6xnc]], [[6xoy]] - StTrpS α + β + IGP + Trp derivative<br /> | |||
**[[7lut]] - StTrpS α + β + PLP + Trp <br /> | |||
**[[6usa]] - MtTrpS α + β + PLP derivative + piperazine derivative<br /> | |||
*Tryptophan synthase α+β quaternary complex | *Tryptophan synthase α+β quaternary complex | ||
**[[1a5s]] - StTrpS α + β + | **[[1a5s]] - StTrpS α + β + Ser + inhibitor + PLP<br /> | ||
**[[5cgq]] - StTrpS α + β + Trp + inhibitor + PLP<br /> | **[[5cgq]], [[7lkl]], [[7ltp]] - StTrpS α + β + Trp + inhibitor + PLP<br /> | ||
**[[7lv5]] - StTrpS α + β + His + inhibitor + PLP<br /> | |||
**[[7jll]] - StTrpS α + β (mutant) + Trp + inhibitor + PLP<br /> | |||
**[[3cep]] - StTrpS α + β + G3P + indoline + PLP<br /> | **[[3cep]] - StTrpS α + β + G3P + indoline + PLP<br /> | ||
**[[6uap]], [[6ub9]], [[6dwe]], [[6e9p]] - MtTrpS α + β + malonate + inhibitor + PLP derivative<br /> | **[[6uap]], [[6ub9]], [[6dwe]], [[6e9p]] - MtTrpS α + β + malonate + inhibitor + PLP derivative<br /> | ||
**[[6u6c]] - MtTrpS α + β + PLP derivative + sulfonamide derivative + Ala<br /> | |||
*Dimethylallyl tryptophan synthase or tryptophan 6-prenyltransferase | |||
**[[3i4z]] - AfDATrpS – ''Aspergillus fumigatus''<br /> | |||
**[[3i4x]] - AfDATrpS + DMAPP + Trp<br /> | |||
**[[4ld7]] - DATrpS + thiopyrophosphate – ''Neosartoria fischeri<''br /> | |||
**[[6zs0]] - ScDATrpS – Stretptomyces coelicolor<br /> | |||
**[[5inj]], [[6zrz]], [[7w8v]], [[7w8w]], [[7w8x]] - ScDATrpS + DMASPP + Trp<br /> | |||
**[[7y8y]] - ScDATrpS + thiopyrophosphate + DMASPP + Trp<br /> | |||
**[[6zry]] - MoDATrpS + Trp – ''Micromonospora olivasterospora''<br /> | |||
**[[6zrx]] - MoDATrpS + DMAPP + Trp<br /> | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Latest revision as of 13:38, 29 January 2024
3D structures of tryptophan synthase3D structures of tryptophan synthase
Updated on 29-January-2024 - For a general description of the protein see Tryptophan synthase
- 1ttp, 1ttq, 1bks, 2wsy, 1kfk, 7l4d, 7lx1, 8b03 - StTrpS α + β + PLP
- 6dz4, 8b05, 8b08 - StTrpS α + β + PLP derivative
- 1k7x, 2j9z, 7kmc, 7l47 - StTrpS α + β (mutant) + PLP
- 3pr2, 4hn4, 4hpj, 4hpx, 4ht3, 4kkx, 7kwv, 7kxc, 7kyt, 7l03 - StTrpS α + β + inhibitor
- 1kfj - StTrpS α + β + pyridoxal-serine-monophsphate
- 1a5a, 1k8x - StTrpS α (mutant) + β + PLP
- 1kfe - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate
- 7ku9, 7l1h, 7lgx, 7mt4, 7mt5, 7mt6 - StTrpS α + β + inhibitor
- 6o1h, 6dzo, 6duc, 6d0v, 6c73, 6x0c, 7jmq, 7kbn, 7ki7 - StTrpS α + β (mutant) + inhibitor
- 2j9y, 7lt4 - StTrpS α + β (mutant) + enoic acid derivative
- 6xrh, 6xt0 - StTrpS α + β (mutant) + IGP + Ala derivative
- 7jqw, 7k5a - StTrpS α + β (mutant) + Ser
- 2tys - StTrpS α (mutant) + β (mutant) + Trp derivative
- 5kzm - TrpS α + β + PLP derivative – Francisella tularensis
- 5kin - SpTrpS α + β + PLP derivative – Streptococcus pneumoniae
- 5e0k - PfTrpS α + β + PLP derivative
- 5ocw, 5tcg, 5tci, 5tcj - MtTrpS α + β + inhibitor
- 5tcf - MtTrpS α + β + PLP derivative
- 5tch - MtTrpS α + β (mutant) + PLP derivative
- 5e0k - PfTrpS α + β + PLP derivative
- 5ey5 - TrpS α + β + PLP - synthetic
- 1ttp, 1ttq, 1bks, 2wsy, 1kfk, 7l4d, 7lx1, 8b03 - StTrpS α + β + PLP
- Tryptophan synthase α+β ternary complex with PLP and inhibitor
- 1a50, 1cw2, 1c9d, 1cx9, 1c8v, 1c29, 2cle, 2clh, 2cli, 2clk, 2cll, 2clm, 2clo, 2clf, 5bw6, 4zqc, 4y6g, 4xug, 4wx2, 5bw6, 6vnt, 6wx3, 6xin, 7kqf, 7lpf, 7lvx, 7ly8, 7m2l, 7m3s, 7me8 - StTrpS α + β + inhibitor + PLP
- 1fuy, 7jhw, 7kh6 - StTrpS α + β (mutant) + inhibitor + PLP
- 6xe3 - StTrpS α + β (mutant) + inhibitor + PLP derivative
- 1a50, 1cw2, 1c9d, 1cx9, 1c8v, 1c29, 2cle, 2clh, 2cli, 2clk, 2cll, 2clm, 2clo, 2clf, 5bw6, 4zqc, 4y6g, 4xug, 4wx2, 5bw6, 6vnt, 6wx3, 6xin, 7kqf, 7lpf, 7lvx, 7ly8, 7m2l, 7m3s, 7me8 - StTrpS α + β + inhibitor + PLP
- Tryptophan synthase α+β ternary complex with PLP and IGP derivatives
- 1a5b, 1kfb - StTrpS α (mutant) + β + IGP + PLP
- 1k8z - StTrpS α + β (mutant) + IGP derivative + PLP
- 1kfc - StTrpS α (mutant) + β + IGP derivative + PLP
- 1k3u, 1k7e, 1k7f - StTrpS α + β + IGP derivative + PLP
- 1qoq, 2rh9, 2rhg - StTrpS α + β + IGP + PLP
- 1qop - StTrpS α + β + IGP analog + PLP
- 2trs, 1beu - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + IGP analog
- 1a5b, 1kfb - StTrpS α (mutant) + β + IGP + PLP
- Tryptophan synthase α+β ternary complex with PLP and G3P derivatives
- Other TrpS α+β ternary complex
- 6hul - SsTrpS α + β subunits + PLP + Ser
- 8b06 - StTrpS α + β + Ser + PLP
- 7k0b - StTrpS α + β (mutant) + Ser + PLP
- 1ubs - StTrpS α (mutant) + β (mutant) + Ser + PLP
- 7jtt, 7ka1 - StTrpS α + β (mutant) + Ser + inhibitor
- 6vfd - StTrpS α + β + quinoid derivative + Ser
- 6xnc, 6xoy - StTrpS α + β + IGP + Trp derivative
- 7lut - StTrpS α + β + PLP + Trp
- 6usa - MtTrpS α + β + PLP derivative + piperazine derivative
- 6hul - SsTrpS α + β subunits + PLP + Ser
- Tryptophan synthase α+β quaternary complex
- 1a5s - StTrpS α + β + Ser + inhibitor + PLP
- 5cgq, 7lkl, 7ltp - StTrpS α + β + Trp + inhibitor + PLP
- 7lv5 - StTrpS α + β + His + inhibitor + PLP
- 7jll - StTrpS α + β (mutant) + Trp + inhibitor + PLP
- 3cep - StTrpS α + β + G3P + indoline + PLP
- 6uap, 6ub9, 6dwe, 6e9p - MtTrpS α + β + malonate + inhibitor + PLP derivative
- 6u6c - MtTrpS α + β + PLP derivative + sulfonamide derivative + Ala
- 1a5s - StTrpS α + β + Ser + inhibitor + PLP
- Dimethylallyl tryptophan synthase or tryptophan 6-prenyltransferase
- 3i4z - AfDATrpS – Aspergillus fumigatus
- 3i4x - AfDATrpS + DMAPP + Trp
- 4ld7 - DATrpS + thiopyrophosphate – Neosartoria fischeri<br />
- 6zs0 - ScDATrpS – Stretptomyces coelicolor
- 5inj, 6zrz, 7w8v, 7w8w, 7w8x - ScDATrpS + DMASPP + Trp
- 7y8y - ScDATrpS + thiopyrophosphate + DMASPP + Trp
- 6zry - MoDATrpS + Trp – Micromonospora olivasterospora
- 6zrx - MoDATrpS + DMAPP + Trp
- 3i4z - AfDATrpS – Aspergillus fumigatus