3j5y: Difference between revisions
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==Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP== | ==Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP== | ||
< | <SX load='3j5y' size='340' side='right' viewer='molstar' caption='[[3j5y]], [[Resolution|resolution]] 9.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3j5y]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3j5y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3j2k 3j2k]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J5Y FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.7Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j5y OCA], [https://pdbe.org/3j5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j5y RCSB], [https://www.ebi.ac.uk/pdbsum/3j5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j5y ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/ERF1_HUMAN ERF1_HUMAN] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.<ref>PMID:7990965</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3j5y" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Frank | [[Category: Frank J]] | ||
[[Category: Grassucci RA]] | |||
[[Category: Grassucci | [[Category: Hashem Y]] | ||
[[Category: Hashem | [[Category: Hellen CUT]] | ||
[[Category: Hellen | [[Category: Pestova TV]] | ||
[[Category: Pestova | [[Category: Taylor D]] | ||
[[Category: Taylor | [[Category: Unbehaun A]] | ||
[[Category: Unbehaun | [[Category: Des Georges A]] | ||
[[Category: | |||
Latest revision as of 17:16, 24 January 2024
Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNPStructure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
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